FGF21, a hormone created in the liver in response to increased levels of sugar, acts in the brain to suppress sugar intake and controls the preference for sweet-tasting foods.
Researchers have identified specific neurons and networks that regulate 'sundowning', a phenomenon commonly seen in Alzheimer's patients who exhibit worsening confusion and aggression levels at the end of the day.
Researchers report on why some people may experience increasing levels of aggression at the end of the day. The study reports the scientists have developed new gene editing tools to help turn of cells that cause sundowning behaviors.
Researchers have uncovered a neural mechanism in female mice that shifts estrogen from playing a protective role in glucose metabolism to a disruptive one.