Researchers have identified 579 genetic loci associated with increased risk of disorders associated with self-regulation disorders including addiction, ADHD, and anti-social behavior.
Belief in conspiracy theories is causing problems within families and other close relationships. The growth of conspiratorial belief may be a result of social media outlets making it easier for those who believe in conspiracies to find other believers and share misinformation. Researchers say discussing your concerns for those close to you who believe in conspiracies requires a very careful approach.
Study reveals blunted activity in the medial prefrontal cortex was associated with aggressive behaviors by abusive partners in relationships.
Two existing medications show promise in the treatment of the deadly childhood cancer, neuroblastoma. Phenformin and AZD3965 exploit the metabolic hunger of the disease to kill cancer cells without inflicting excessive damage to healthy tissue.
Study shows how cholesterol becomes dysregulated in brain cancer cells and reports the gene responsible for the dysregulation could be a potential target to help treat glioblastoma brain cancer.
Aggression toward members in an "outgroup" was associated with increased activity in areas of the brain associated with reward. Activity in the ventromedial prefrontal cortex impacted the level of aggression a person demonstrated against an outsider.
Epigenetic traces of childhood trauma can be used as biomarkers to predict the risk of addiction, depression, and a range of other physical and mental health issues 17 years later.
FIASMA antidepressants, such as amitriptyline and desipramine, halt the growth of four different kinds of bacterial pathogens in cell cultures and animal models. The antidepressants have shown to be effective in killing intracellular bacteria in two chlamydia infections, as well as human granulocytic anaplasmosis, a tick-borne disease that attacks white blood cells.
While psychopathy is generally associated with antisocial behaviors, many with the personality trait develop successful careers. A new study supports a novel model of psychopathy which runs contradictory to existing models of the disorder, focusing on the strengths associated with psychopathy, rather than just the deficits. Researchers found higher initial psychopathy was associated with a steeper increase of general inhibitory control and the inhibition of aggression over time. The effect was magnified among those who were "successful."
Researchers argue COVID-19 should be considered as an inflammatory disease as the severity of the infection is associated with a dysregulation of the inflammatory immune response.