Study identified 300 "hub genes" that appear to control separate gene networks in brain tissue samples. The SAMD3 gene appears to be a master regulator to control the activity of many of the gene hubs and the genes the hubs control.
Researchers have made a surprise discovery that could help provide treatment options for a range of conditions from Parkinson's disease to depression. Researching how to transform supportive brain cells into neurons, the scientists unexpectedly transformed mature inhibitory striatal neurons into dopamine producing neurons.
Study reports a link between levels of GlycA, an inflammatory molecule in the blood, and an increased risk of depression symptoms. Researchers also outline specific symptoms associated with menopause and an increased likelihood of developing depression.