UT Southwestern Medical Center

Random

UT Southwestern Medical Center

Featured Genetics Neuroscience Open Neuroscience Articles

·October 11, 2018·4 min read

Researchers Unexpectedly Reprogram Mature Neurons in Mice

Researchers have made a surprise discovery that could help provide treatment options for a range of conditions from Parkinson's disease to depression. Researching how to transform supportive brain cells into neurons, the scientists unexpectedly transformed mature inhibitory striatal neurons into dopamine producing neurons.

This is an abstract art drawing of a dead and the hippocampus

Featured Genetics Neuroscience

·May 28, 2021·4 min read

Two Halves of the Hippocampus Have Different Gene Activity

Researchers have identified significant differences in gene activity between the anterior and posterior areas of the hippocampus. Genes associated with depression and other mood disorders are more active in the anterior hippocampus, while genes linked to cognitive disorders, such as ASD, are more active in the posterior hippocampus.

Featured Genetics Neurology

·August 12, 2020·4 min read

‘Reelin’ in a New Treatment for Multiple Sclerosis

Decreasing the amount of Reelin significantly protected against disease symptoms and promoted recovery in symptomatic animal models of multiple sclerosis. Reelin levels appear to correlate with MS severity and stages. Researchers report lowering levels of the protein could be a potential avenue of treatment for the autoimmune disorder.

Featured Genetics Neurology Open Neuroscience Articles

·November 21, 2018·6 min read

DNA Vaccine Reduces Both Toxic Proteins Linked to Alzheimer’s

A new DNA vaccine tested in mice significantly reduces tau and amyloid beta, two proteins implicated in Alzheimer's disease. The findings, researchers say, may pave the way for clinical trials in humans with the neurodegenerative disease.

Featured Neuroscience Open Neuroscience Articles

·July 18, 2017·4 min read

Eating at ‘Wrong Time’ Affects Body Weight and Circadian Rhythm

Eating late, or at inappropriate times might have a significant impact on both weight and normal sleep-wake patterns, a new study published in Cell Metabolism reports.

Featured Genetics Neuroscience

·June 14, 2018·6 min read

Brain Changes Linked to Sleep Needed

A new study sheds light on the biochemistry of sleep need in the brain.

Featured Neurology Neuroscience Open Neuroscience Articles

·December 11, 2018·4 min read

New Discoveries Predict Ability to Forecast Dementia From Single Molecule

Researchers report single tau proteins have different shapes, and the folds of the molecules could help doctors to predict which type of dementia a person is likely to suffer from.

Featured Neurology

·October 28, 2016·6 min read

Structure of Toxic Tau Aggregates Determines Type of Dementia, Rate of Progression

A new study may help shed light on the diversity of dementias linked to tau protein aggregation.

Featured Genetics Neuroscience

·March 10, 2021·5 min read

Key Genes in the Brain Involved in Encoding Memories Identified

Study identified 300 "hub genes" that appear to control separate gene networks in brain tissue samples. The SAMD3 gene appears to be a master regulator to control the activity of many of the gene hubs and the genes the hubs control.

Featured Genetics Neuroscience

·December 6, 2017·5 min read

CLOCK Gene May Hold Answers to Human Brain Evolution

UT Southwestern researchers discover a gene implicated in circadian rhythm may also play a vital role in regulating genes important for our brain evolution.

This is an illustration of amyloid beta in neurons

Featured Neurology Neuroscience

·September 17, 2019·5 min read

Exercise could slow withering effects of Alzheimer’s

For those with mild cognitive impairment (MCI) and other risk factors for Alzheimer's disease, participating in aerobic exercise several times a week may slow neurodegeneration. Aerobic exercise reduced hippocampal atrophy in those with MCI.

Featured Neurology Neuroscience

·May 21, 2020·4 min read

Exercise improves memory and boosts blood flow to brain

Following a one year program of aerobic exercise improves memory function and boosts blood flow to brain areas critical for cognition in older adults with risk factors for dementia.

1 2