Researchers have made a surprise discovery that could help provide treatment options for a range of conditions from Parkinson's disease to depression. Researching how to transform supportive brain cells into neurons, the scientists unexpectedly transformed mature inhibitory striatal neurons into dopamine producing neurons.
Researchers have identified significant differences in gene activity between the anterior and posterior areas of the hippocampus. Genes associated with depression and other mood disorders are more active in the anterior hippocampus, while genes linked to cognitive disorders, such as ASD, are more active in the posterior hippocampus.
Decreasing the amount of Reelin significantly protected against disease symptoms and promoted recovery in symptomatic animal models of multiple sclerosis. Reelin levels appear to correlate with MS severity and stages. Researchers report lowering levels of the protein could be a potential avenue of treatment for the autoimmune disorder.
A new DNA vaccine tested in mice significantly reduces tau and amyloid beta, two proteins implicated in Alzheimer's disease. The findings, researchers say, may pave the way for clinical trials in humans with the neurodegenerative disease.
Eating late, or at inappropriate times might have a significant impact on both weight and normal sleep-wake patterns, a new study published in Cell Metabolism reports.
Researchers report single tau proteins have different shapes, and the folds of the molecules could help doctors to predict which type of dementia a person is likely to suffer from.
A new study may help shed light on the diversity of dementias linked to tau protein aggregation.
Study identified 300 "hub genes" that appear to control separate gene networks in brain tissue samples. The SAMD3 gene appears to be a master regulator to control the activity of many of the gene hubs and the genes the hubs control.
UT Southwestern researchers discover a gene implicated in circadian rhythm may also play a vital role in regulating genes important for our brain evolution.
For those with mild cognitive impairment (MCI) and other risk factors for Alzheimer's disease, participating in aerobic exercise several times a week may slow neurodegeneration. Aerobic exercise reduced hippocampal atrophy in those with MCI.
Following a one year program of aerobic exercise improves memory function and boosts blood flow to brain areas critical for cognition in older adults with risk factors for dementia.