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University of Pennsylvania

·July 29, 2020·6 min read

Getting Gene Therapy to the Brain

Researchers successfully applied a gene therapy platform to completely correct brain defects in a large animal model of a human genetic disease.

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Autism Featured Neuroscience Open Neuroscience Articles

·July 7, 2020·4 min read

Sensory Neurons Outside the Brain Drive Autistic Social Behaviors

The loss of the protein neurofibromin 1 (NF1) in adult male flies resulted in social impairments. The deficits were traced back to a primary disruption in a small group of peripheral neurons which control external stimuli, including touch and smell, that communicate to the brain.

Featured Neurology Neuroscience Open Neuroscience Articles

·March 27, 2020·7 min read

A new way to study HIV’s impact on the brain

HIV infection leads to increased EIF2 signaling in microglia, astrocytes, and neurons. Study reveals how HIV infection and some antiretrovirals affect cognition and the central nervous system.

Featured Neurology Neuroscience Open Neuroscience Articles

·March 11, 2020·4 min read

Common muscle relaxant given via nose shows potential to treat Alzheimer’s

Dantrolene, a common muscle relaxant, shows promise in the treatment of Alzheimer's disease. Mice administered the drug intranasally had higher concentrations of the medicine in their brains, and for longer periods, than those who received it orally. The drug has been shown to help inhibit or slow the progression of several neurodegenerative diseases.

Featured Neuroscience Psychology

·March 1, 2020·6 min read

Second Type of Schizophrenia Discovered

Combining neuroimaging data with artificial intelligence, researchers have identified two distinct neuroanatomical subtypes of schizophrenia. The first, more typical subtype is associated with a lower widespread volume of gray matter compared to healthy controls. In the second subtype, gray matter volume is largely similar to healthy brains.

Featured Neuroscience

·February 19, 2020·5 min read

Machine learning identifies personalized brain networks in children

Study shows how brain networks unique to each child can predict cognition. Using a combination of neuroimaging data and machine learning, researchers reveal functional neuroanatomy can vary greatly among children and is refined during development.

Featured Genetics Neuroscience

·February 19, 2020·4 min read

Bmal1 gene is not an essential regulator of circadian rhythms

Deleting the circadian rhythm-associated BMAL1 gene in animal models, researchers discovered tissue continued to follow a 24-hour rhythm, even in the absence of external stimuli that can influence the cycle.

Featured Neuroscience Open Neuroscience Articles Psychology

·January 19, 2020·5 min read

No clear evidence of increase in adolescent suicide after ’13 Reasons Why’

Contrary to the initial findings, a reanalysis of data from a 2019 study found no clear relationship between a rise in teenage suicide and the Netflix show "13 Reasons Why".

Featured Neuroscience Open Neuroscience Articles Psychology

·January 6, 2020·5 min read

A new link between fear, imitation, and antisocial behavior in children

Children who exhibit less fear and desire for social connection, and who engage less in imitative behaviors, are more likely to develop callous-unemotional traits which may later lead to antisocial behaviors.

Featured Neuroscience Open Neuroscience Articles Psychology

·November 4, 2019·5 min read

Anger, anxiety, insomnia: Tweets from Twitter users could predict loneliness

Linguistic analytic models found users who tweet about loneliness post significantly more frequently about mental health concerns, relationship problems, and insomnia.