Researchers have identified a potential new drug target for COVID-19. The scientists mapped the anatomical structures of two critical SARS-CoV-2 proteins in the nsp10/nsp16 complex. If a drug can be developed to inhibit nsp10/nsp16, researchers believe the immune system should be able to detect the infection and eradicate it faster.
Study finds olfaction plays a significant role in the motivation to exercise. Mice who were "high runners" developed genetic differences in their olfactory systems that caused them to perceive smells differently than more sedentary mice.
Mouse study pinpoints the precise location in the brain where distracting stimuli are blocked, allowing for concentration on specific tasks. The findings could have implications for the treatment of ADHD and schizophrenia.
Male alcohol consumption before conception was linked to significant deficits in their offspring's brain development, specifically within the neocortex. For mothers-to-be who drink alcohol, the negative outcomes of prenatal alcohol exposure on fetal brain development can be reduced with choline supplementation.
Female mice exposed to PBDEs, a type of flame-retardant found on everyday household items, pass on the chemicals to their developing offspring. In female offspring, this can cause alterations in social memories and behaviors which are reminiscent of human compulsive behaviors associated with autism.
Researchers discovered how the TGF-beta protein controls the process by which hair follicles, including stem cells, divide and form new cells or orchestrate apoptosis. The findings could provide new treatment options for baldness and therapies to speed up wound healing.
Children with the APOE E4 gene perform lower on verbal and general IQ tests than their peers without the genetic risk factor. APOE E4 is a genetic risk factor for Alzheimer's disease. The study suggests the effects of the gene manifests before adulthood and could be the earliest biomarker for later vulnerability to Alzheimer's disease.
Findings could lead to the development of new treatments to reduce the effects of PTSD, researchers say.