Increased levels of epoxide hydrolase in the prefrontal cortex were found in the brains of young mice whose mothers had suffered infection during pregnancy. Inhibiting epoxide hydrolase reverses cognitive and social deficits associated with neurodevelopmental disorders, such as ASD.
H2CBD, a synthetic version of the cannabis compound CBD, has been found to be effective in decreasing the number and severity of seizures in rats.
Boosting neurotrophin-3 in non-human primates changes dispositional anxiety. The findings could pave the way for new treatments to curb anxiety in humans.
Aerosolized particles produced while speaking may be enough to transmit coronavirus infection by those who are asymptomatic.
Maternal inflammation has been linked to a range of neurodevelopmental and psychiatric disorders in children, including autism and schizophrenia. A new mouse study reveals maternal responses and subsequent developmental disorders are based on the mother's immunoreactivity to infection.
A new study reveals up to 30% of children diagnosed with autism had less severe symptoms at age six than they did at age three. In some cases, children lost their autism diagnoses entirely. Girls are more likely to show a greater reduction in autism symptoms and less of a rise in the severity of symptoms than boys on the autism spectrum.
Fragile X syndrome patients with prematuration had a much earlier onset of neurological problems, including earlier symptoms of neurodegeneration. They also experienced emotional processing problems. Some of the most common emotional processing disorders reported were mood regulation, anxiety, and psychosis.
When it comes to decision making, researchers discovered toddlers experience and deal with uncertainty in the same way as older children and adults.
Preschool-aged children on the autism spectrum were 2.7 times more likely to experience gastrointestinal problems, including pain, diarrhea, constipation, and vomiting than their typically developing peers. Almost 50% of those with ASD reported frequent GI symptoms, compared to 18% of those without the disorder. 30% of autistic children experienced multiple GI symptoms. Multiple GI problems were associated with sleep and attention problems, as well as self-harm, aggression, and repetitive behaviors in both children with ASD and those not on the autism spectrum.
Children born to mothers who experienced immune disorders during pregnancy, including allergies, asthma, autoimmune diseases, and autoinflammatory syndromes, are more likely to exhibit behavioral and emotional problems. The child's sex may interact with maternal immune conditions to influence the outcome of ASD symptoms. While maternal immune disorders were associated with emotional and behavioral problems in children on the autism spectrum, there was no association with reduced cognitive function.
People formulate personal goals consistent with their personality traits, and their goals are related to how their personality changes over time.
Study links diabetic ketoacidosis to lower IQ scores and worse memory in children with type 1 diabetes.