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TDP-43

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Featured Genetics Neurology Neuroscience

·February 28, 2022·4 min read

A New Molecular Pathway Shared by Two Neurodegenerative Disorders Discovered

Mislocalization of the TDP-43 protein alters the genetic instructions for UNC13A. The findings provide a potential new therapeutic target for the treatment of ALS and frontotemporal dementia.

Featured Neurology

·September 30, 2016·3 min read

Abnormal Brain Protein May Contribute to Development of Alzheimer’s

A new study reports on the role the protein TDP-43 plays in the development of Alzheimer's disease.

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Featured Neurology

·August 26, 2015·4 min read

Awareness of Memory Loss Can Decline Up To Three Years Before Alzheimer’s Onset

A new study reports people may lose awareness of their memory loss almost three years prior to Alzheimer's disease setting in.

Featured Genetics Neurology

·March 19, 2018·5 min read

Better Understanding ALS by Looking at How Cells Change

A new study sheds light on the molecular mechanisms behind ALS.

Featured Neurology

·February 20, 2018·4 min read

Brain Immune System is Key to Recovery from Motor Neuron Degeneration

Researchers report microglia is critical for neuronal survival in ALS.

This image shows a retina cross section from a healthy mouse.

Electrophysiology Featured Genetics

·August 25, 2014·3 min read

Changes in the Eye Can Predict Changes in the Brain

Researchers report retinal degeneration could be one of the earliest signs of FTD in people who have a genetic risk for the disorder.

Featured Neurology Neuroscience

·April 20, 2023·5 min read

Cognitive Decline May Be Triggered by Astrocyte Dysfunction

A new study reveals astrocyte dysfunction may be a driver of cognitive decline and memory loss in those with dementia. This may be caused by a protein build-up in the astrocytes that appears to trigger abnormal antiviral activity that results in memory loss.