Mislocalization of the TDP-43 protein alters the genetic instructions for UNC13A. The findings provide a potential new therapeutic target for the treatment of ALS and frontotemporal dementia.
A new study reports on the role the protein TDP-43 plays in the development of Alzheimer's disease.
A new study reports people may lose awareness of their memory loss almost three years prior to Alzheimer's disease setting in.
A new study sheds light on the molecular mechanisms behind ALS.
Researchers report microglia is critical for neuronal survival in ALS.
Researchers report retinal degeneration could be one of the earliest signs of FTD in people who have a genetic risk for the disorder.
Research using C. elegans finds maple syrup may protect neurons and prevent the development of ALS.
A new mouse model has been developed that captures the pathology of sporadic neurodegenerative diseases.
Researchers discover reactivating ancient viral genes may cause neuron destruction in some forms of ALS.
Researchers have developed a new model to study neurodegenerative diseases which affect motor neurons, such as ALS.
A new study reveals many inhibitory neurons are lost in early phases of ALS and FTD development. The findings show a contrast to other neurodegenerative diseases where excitatory neurons are lost early in the disorders.
Researchers have identified a genetic mutation associated with both ALS and frontotemporal dementia.
