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          TDP-43

          This shows the outline of a head and a question mark
          FeaturedGeneticsNeurologyNeuroscience
          ·February 28, 2022·4 min read

          A New Molecular Pathway Shared by Two Neurodegenerative Disorders Discovered

          Mislocalization of the TDP-43 protein alters the genetic instructions for UNC13A. The findings provide a potential new therapeutic target for the treatment of ALS and frontotemporal dementia.
          Read More
          Image of an Alzheimer's brain slice.
          FeaturedNeurology
          ·September 30, 2016·3 min read

          Abnormal Brain Protein May Contribute to Development of Alzheimer’s

          A new study reports on the role the protein TDP-43 plays in the development of Alzheimer's disease.
          Read More
          This image shows the brain of an alzheimer's patient.
          FeaturedNeurology
          ·August 26, 2015·4 min read

          Awareness of Memory Loss Can Decline Up To Three Years Before Alzheimer’s Onset

          A new study reports people may lose awareness of their memory loss almost three years prior to Alzheimer's disease setting in.
          Read More
          cells
          FeaturedGeneticsNeurology
          ·March 19, 2018·5 min read

          Better Understanding ALS by Looking at How Cells Change

          A new study sheds light on the molecular mechanisms behind ALS.
          Read More
          neurons
          FeaturedNeurology
          ·February 20, 2018·4 min read

          Brain Immune System is Key to Recovery from Motor Neuron Degeneration

          Researchers report microglia is critical for neuronal survival in ALS.
          Read More
          This image shows a retina cross section from a healthy mouse.
          ElectrophysiologyFeaturedGenetics
          ·August 25, 2014·3 min read

          Changes in the Eye Can Predict Changes in the Brain

          Researchers report retinal degeneration could be one of the earliest signs of FTD in people who have a genetic risk for the disorder.
          Read More
          This shows astrocytes at a synapse
          FeaturedNeurologyNeuroscience
          ·April 20, 2023·5 min read

          Cognitive Decline May Be Triggered by Astrocyte Dysfunction

          A new study reveals astrocyte dysfunction may be a driver of cognitive decline and memory loss in those with dementia. This may be caused by a protein build-up in the astrocytes that appears to trigger abnormal antiviral activity that results in memory loss.
          Read More
          Image of a C. elegans.
          FeaturedNeurology
          ·April 13, 2016·4 min read

          Could Maple Syrup Help Protect Against Development of ALS?

          Research using C. elegans finds maple syrup may protect neurons and prevent the development of ALS.
          Read More
          brain slices
          FeaturedGeneticsNeurologyOpen Neuroscience Articles
          ·November 13, 2017·4 min read

          Deadly Combination in Neurodegenerative Diseases Revealed

          A new mouse model has been developed that captures the pathology of sporadic neurodegenerative diseases.
          Read More
          This shows DNA
          FeaturedGeneticsNeurologyNeuroscience
          ·March 16, 2023·5 min read

          DNA Treatment Could Delay Paralysis That Strikes Nearly All Patients With ALS

          DNA designer therapeutics restored levels of a protein critical to motor neuron function, restoring the activity that is impaired as a result of ALS.
          Read More
          Image shows stained mouse brain slice. The caption provides more information.
          FeaturedNeurologyNeuroscience Videos
          ·September 30, 2015·3 min read

          Dormant Viral Gene May Cause Some Forms of ALS

          Researchers discover reactivating ancient viral genes may cause neuron destruction in some forms of ALS.
          Read More
          This shows a neuron.
          FeaturedGeneticsNeurologyNeuroscience
          ·March 12, 2026·7 min read

          Five High-Risk Neuron Groups Identified in ALS and FTD

          New research reveals five specific types of neurons that are the primary targets of ALS and FTD, paving the way for cell-specific therapies.
          Read More
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          A 3D digital rendering showing a developing fetal brain connected by glowing neural pathways and floating DNA strands, surrounded by subtle immune cells.

          How Severe Illness During Pregnancy Alters Fetal Brain Development

          A 3D digital illustration of a human brain side-by-side comparison, highlighting the language centers glowing brightly and equally in both a younger and older brain, while executive function areas are dimmed in the older brain.

          Aging Brains Maintain Robust Language Networks Despite Cognitive Decline

          Rejuvenation of Microglia by Youth Protein TIMP2 in the Aging Brain

          Youth Protein TIMP2 Restores Immune Function in the Aging Brain

          A multi-panel documentary photo. Left: A Black man sits alone on a locker room bench with his head down. Center: A Latino man sits withdrawn at a family kitchen table. Right: A White man looks thoughtfully at wellness pamphlets in a public waiting area. All convey isolation.

          Shame, Stigma, and Culture Prevent Male Domestic Violence Survivors From Seeking Help

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