FeaturedGeneticsNeurologyNeuroscience·December 4, 2023·4 min readThe Role of Protein Misfolding in Neurodegenerative DiseasesNeurodegenerative diseases share a common factor: protein misfolding and deposits in the brain. Misfolded proteins can lead to toxic activity or the loss of the protein's physiological function, causing damage to neurons.Read More
FeaturedNeurologyNeuroscience·April 20, 2023·5 min readCognitive Decline May Be Triggered by Astrocyte DysfunctionA new study reveals astrocyte dysfunction may be a driver of cognitive decline and memory loss in those with dementia. This may be caused by a protein build-up in the astrocytes that appears to trigger abnormal antiviral activity that results in memory loss.Read More
FeaturedGeneticsNeurologyNeuroscience·March 16, 2023·5 min readDNA Treatment Could Delay Paralysis That Strikes Nearly All Patients With ALSDNA designer therapeutics restored levels of a protein critical to motor neuron function, restoring the activity that is impaired as a result of ALS.Read More
FeaturedNeuroscience·November 29, 2022·3 min readKey Factors Identified for Regeneration of Brain TissueResearchers have identified two proteins that prevent the formation of scars in the brain and help promote the regeneration of new neural tissue.Read More
FeaturedNeurologyNeuroscience·July 21, 2022·6 min readSigns of Alzheimer’s in Blood 17 Years Before Symptoms BeginA newly developed immuno-infrared sensor allowed researchers to discover biomarkers for Alzheimer's disease in blood samples 17 years before clinical symptoms appeared. The sensory is able to detect the misfolding of amyloid beta.Read More
FeaturedNeurologyNeuroscience·May 27, 2022·4 min readOn Your Back, Side, or Face-Down? How We Sleep May Trigger or Protect Our Brain From Diseases Like ALSA new mouse study reveals our sleep position may influence the glymphatic system and could increase the risk of developing ALS or other neurodegenerative diseases.Read More
FeaturedGeneticsNeurologyNeuroscience·February 28, 2022·4 min readA New Molecular Pathway Shared by Two Neurodegenerative Disorders DiscoveredMislocalization of the TDP-43 protein alters the genetic instructions for UNC13A. The findings provide a potential new therapeutic target for the treatment of ALS and frontotemporal dementia.Read More
FeaturedGeneticsNeurologyNeuroscience·January 9, 2022·3 min readResearch Clears up How Brain ‘Cleaners’ Fail in ALSFindings point to microglial TREM2 as a potential target for the treatment of ALS.Read More
FeaturedGeneticsNeurologyNeuroscience·December 9, 2020·4 min readNew Biomarker Candidate for ALSA novel method detected conformational changes to the TDP-43 protein in cerebral spinal fluid associated with ALS.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·September 8, 2020·5 min readInvestigational Drug Stops Toxic Proteins Tied To ALSc9ASO, an investigational ASO drug, targets the TDP-43 protein, reducing its buildup and decreasing neurological decline associated with ALS and FTD.Read More
FeaturedGeneticsNeurology·August 19, 2020·4 min readPotential Link for Alzheimer’s Disease and Common Brain Disease That Mimics Its SymptomsResearchers identified a group of closely related genes that capture molecular links between Alzheimer's and LATE, a common brain disorder that mimics Alzheimer's symptoms.Read More
FeaturedGeneticsNeurologyNeuroscience·February 11, 2020·4 min readSpeeding up treatments for ALSStudy reports protein aggregates within cells are cleared out by the endocytosis process. The findings could help with the development of new treatments for ALS.Read More
