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          talin

          This shows APP.
          FeaturedNeurologyNeuroscience
          ·March 14, 2024·6 min read

          Unraveling Alzheimer’s: A Novel Mechanical Perspective on Amyloid Precursor Protein’s Role

          groundbreaking study introduces a novel hypothesis that Amyloid Precursor Protein (APP), known for its role in Alzheimer's disease (AD), is crucial for the mechanical integrity of synapses through its interaction with talin, a synaptic scaffold protein. It proposes that the misprocessing of APP disrupts mechanical signaling pathways, leading to synaptic degeneration and memory loss, thereby contributing to the progression of AD.
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          This shows the outline of a woman and a brain surrounded by lightbulbs
          FeaturedGeneticsNeuroscienceOpen Neuroscience Articles
          ·March 1, 2021·4 min read

          A New Theory for How Memories Are Stored in the Brain

          A new theory of memory visualizes the brain as an organic super-computer that runs complex binary code with neurons acting like mechanical computers. The theory is based on the discovery of the protein molecule, talin, which contains switch-like domains that change shape in response to pressure in mechanical force by a cell.
          Read More

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          Brain’s Social Hub Responds to Confusion, Not Just People

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          Why Your Brain Is Better at Gossip Than You Realize

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          Blurry Beginnings Shape Brain’s Visual Pathways

          This shows the hippocampus.

          Human Brains Keep Making Memory Neurons in Adulthood

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