From consolidating memories to cleaning out toxins in the brain that accumulate during waking hours, researchers explore why sleep is so important and what happens when we don't get enough.
An over-production of eIF4E impairs microglial cells, hampering their ability to effectively prune synapses and leading to autism-like behaviors in male mouse models of ASD.
Participating in exercise improved synaptic pruning in mouse models of autism. The study also found microglia dependant synaptic pruning is impaired by maternal inflammation, which has been previously connected to the development of ASD.
Researchers have identified how sexually dimorphic connections arise in the nervous systems of nematode worms.
Researchers investigate how synaptic pruning occurs during development in hopes of discovering how neurodevelopmental and psychiatric disorders occur.
A gene associated with schizophrenia may trigger runaway synaptic pruning during adolescence, a new study reports.
Researchers have directly observed excessive synaptic pruning in cells derived from people with schizophrenia.
Researchers report the frontoparietal network plays a key role in why humans have superior reasoning skills.
Researchers discover proteins that play an important role in the immune system may be responsible for fine tuning motor control during development and reducing motor function as we age.