Study reports significant reduction in gray matter volume in brain regions associated with social cognition for up to two years following birth.
Researchers report adult neurogenesis not only helps increase the number of cells in a neural network, it also promotes plasticity in the existing network. Additionally, they have identified the role the Bax gene plays in synaptic pruning.
From consolidating memories to cleaning out toxins in the brain that accumulate during waking hours, researchers explore why sleep is so important and what happens when we don't get enough.
Researchers investigate how synaptic pruning occurs during development in hopes of discovering how neurodevelopmental and psychiatric disorders occur.
A new electronic microscopy study has captured microglia perform their role in synaptic pruning.
A new study provides further evidence for immune system activation during pregnancy and disruptions in brain development. Many adult diseases, researchers say, may originate during fetal development.
Researchers have directly observed excessive synaptic pruning in cells derived from people with schizophrenia.
Participating in exercise improved synaptic pruning in mouse models of autism. The study also found microglia dependant synaptic pruning is impaired by maternal inflammation, which has been previously connected to the development of ASD.
White matter tracts show increasing maturation with age from the back to the front of the brain. The maturations begin as a child reaches 9-12 years of age. The maturity correlates with a critical and formative period of development.