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synaptic pruning

Featured Open Neuroscience Articles Psychology

·January 2, 2017·10 min read

Babies Exposed to Stimulation Get a Brain Boost

Contrary to popular belief, exposing children to stimuli early can help to boost their development, researchers report.

Featured Genetics Neurology Neuroscience Psychology

·April 17, 2018·2 min read

Brain Development Influenced by Immune System

A new study provides further evidence for immune system activation during pregnancy and disruptions in brain development. Many adult diseases, researchers say, may originate during fetal development.

Featured Neuroscience

·May 16, 2016·4 min read

C. elegans Study Reveals How Differences in Male and Female Brains Emerge

Researchers have identified how sexually dimorphic connections arise in the nervous systems of nematode worms.

Featured Neurology Neuroscience Psychology

·November 5, 2017·4 min read

Why Our Brains Need Sleep, and What Happens If We Don’t Get Enough

From consolidating memories to cleaning out toxins in the brain that accumulate during waking hours, researchers explore why sleep is so important and what happens when we don't get enough.

Autism Featured Genetics

·May 25, 2016·4 min read

Illuminating the Role of Autism Linked Shank Gene

A new study reports a gene mutation linked to autism also plays a critical role when it comes to the formation and maturation of synapses.

This shows neurons in the developing brain

Featured Neuroscience Neuroscience Videos Open Neuroscience Articles

·July 22, 2020·5 min read

New Role for White Blood Cells in the Developing Brain

When T helper cells are absent in the brain, microglia remain suspended between the fetal and adult developmental state. Mice lacking brain T cells showed changes in behavior and defective synaptic pruning. The study reveals the critical role T cells play in the development of the brain.

Electrophysiology Featured Neuroscience Open Neuroscience Articles

·February 3, 2017·4 min read

Brain Plasticity: How Adult Born Neurons Get Wired

Researchers report adult neurogenesis not only helps increase the number of cells in a neural network, it also promotes plasticity in the existing network. Additionally, they have identified the role the Bax gene plays in synaptic pruning.

This image shows a draeing of a brain made up of interconnecting lines to represent a network.

Featured Neuroscience

·July 17, 2015·4 min read

Algorithms Based on Brains Make For Better Networks

Researchers take inspiration from the developing brain to create improved computer algorithms.

This image is a neuron from the brain of a young person with autism.

Autism Electrophysiology Featured

·August 21, 2014·5 min read

Children with Autism Have Extra Synapses in Brain

According to a new study, children with autism have an excess of synapses in the brain, due to a slowdown of the normal pruning process during development.

Featured Neuroscience Psychology

·February 4, 2019·5 min read

Excess Immune Pruning of Synapses in Neural Cells Derived From Patients with Schizophrenia

Researchers have directly observed excessive synaptic pruning in cells derived from people with schizophrenia.

Featured Neuroscience Open Neuroscience Articles

·January 18, 2022·7 min read

Study Highlights Connections Between Addictive Drugs and Brain Function in Mice

Study reveals the specific changes that occur in the brains of mice exposed to cocaine. The findings shed new light on the role of dopamine in addiction, and provide new insight into dopamine transmission in the brain.

Autism Featured Genetics Neuroscience Open Neuroscience Articles

·April 15, 2020·5 min read

Autism in males linked to defect in brain immune cells and microglia

An over-production of eIF4E impairs microglial cells, hampering their ability to effectively prune synapses and leading to autism-like behaviors in male mouse models of ASD.

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