Neural networks play a key role in regulating circadian rhythms through the mediation of cAMP. The findings may help with developing new strategies to manage circadian rhythm problems such as sleep disorders.
Neurons in the suprachiasmatic nucleus coordinate to adapt to different lengths of daylight, changing at cellular and network levels. The neurons changed in mix and expression of dopamine, altering brain activity and subsequently daily routine behaviors.
Mouse study reveals the presence of the Baml1 gene in the striatum has a sexually dimorphic effect on alcohol consumption. Male mice without the protein consumed more alcohol than those who did, while the reverse was true for females.
Daily release of glucocorticoids depends on coordination between the clock gene and activity rhythms of neurons within two parts of the hypothalamus.
The circadian CLOCK gene in the nucleus accumbens shell plays a crucial role in binge drinking behaviors in mouse models.
During wakeful periods, the glymphatic system diverts cerebrospinal fluid to lymph nodes in the neck. The CSF may act as a "fluid clock" that helps initiate the body's infection-fighting capabilities during the day. Astrocytes in the suprachiasmatic nucleus may serve to control CSF through the central nervous system. Communication between astrocytes in different brain regions may optimize the glymphatic system's function as we sleep.
Findings define a connection between reward, dopamine, and circadian pathways in the overeating.
A newly developed microfluidic device allowed researchers to keep tissue from the suprachiasmatic nucleus alive for over 25 days.
Study challenges the widely accepted belief that all light information is relayed through the suprachiasmatic nucleus, which synchronizes the circadian rhythm.
Researchers have unlocked a cure for jet lag by activating VIP neurons in the suprachiasmatic nucleus.
Researchers report proteins associated with immunity and metabolism can become disrupted following just one simulated night shift.
Researchers have found an association between the Per2 gene and breast cancer. The Per2 gene plays an important role in both the body's circadian clock and mammary gland development.
