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SuperAgers

·May 24, 2023·4 min read

Alzheimer’s Pathology Found in Superagers With Superior Cognition

A new study found people who are 90+ and have superior cognitive skills have similar levels of brain pathology as Alzheimer's patients. However, they also have less brain pathology of other neurodegenerative diseases. The researchers are now looking at how lifestyle habits and health conditions are associated with superior cognition in individuals who are 90+.

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·July 1, 2021·5 min read

How Long Can a Person Live? The 21st Century May See a Record-Breaker

Extreme longevity will continue to rise over the 21st Century. Researchers estimate a lifespan of between 125 to 130 years will be possible.

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·November 2, 2017·4 min read

Close Friends Linked to a Sharper Memory

A new PLOS ONE study reports superagers who maintain positive friendships have better cognitive ability and slower memory decline that peers who do not maintain strong social networks.

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·July 1, 2018·3 min read

The Odds of Living to 110 Plus Level Out Once You Hit 105

Researchers report death rates slow after the age of 105. The study reveals there appears to be no fixed limit to the human life span yet in sight.

Featured Neurology Neuroscience

·February 17, 2021·4 min read

SuperAger Brains Resist Protein Tangles That Lead to Alzheimer’s

SuperAgers who maintain their cognitive abilities have resistance to the development of Alzheimer's related tau tangles. The resistance to tangles may help to preserve memory.

Featured Neuroscience

·July 6, 2021·6 min read

Study Reveals Source of Remarkable Memory of “Superagers”

The structure of SuperAgers' brains and the connectivity of their neural networks more closely resembles the brains of younger adults, a neuroimaging study reveals.

Image shows brain shrinkage is an aging brain.

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·April 4, 2017·4 min read

SuperAger Brains Shrink More Slowly Than Peers’ Brains

Typical agers lose brain volume twice as fast as SuperAgers, a new study reports.

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·May 5, 2020·3 min read

People aged 95 and over show stronger brain connectivity

Superagers, people aged 95 and older, showed more activation between their left and right frontoparietal control network in their brains than their younger counterparts. The superior connectivity contributed to better performance on visuospatial cognitive tasks, a new study reports.

Featured Genetics Neurology Neuroscience

·July 25, 2026·8 min read

Alzheimer Genetic Risk Scores Do Not Explain SuperAging

A new study demonstrates that SuperAgers cannot be distinguished from cognitively average peers by APOE status or polygenic risk scores.

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·January 4, 2019·13 min read

The Mysteries of the Super-Ager Revealed

Scientific research is helping to unlock the secrets behind why some people live to become super-agers. Researchers propose ways in which we can slow the aging process and extend our life spans.

Featured Neuroscience

·March 31, 2023·5 min read

Centenarians Possess Unique Immunity That Helps Them Achieve Exceptional Longevity

Centenarians harbor a unique immune cell type, immune activity, and highly functioning immune system that has adapted to a history of illness, allowing for exceptional longevity.

Featured Neuroscience

·August 9, 2025·5 min read

Why Some 80-Year-Olds Have the Memory of 50-Year-Olds

For 25 years, scientists have studied “SuperAgers”—people aged 80 and above whose memory rivals those decades younger. Research reveals that their brains either resist Alzheimer’s-related plaques and tangles or remain resilient despite having them.