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          SuperAgers

          Image shows brain shrinkage is an aging brain.
          FeaturedNeurologyNeuroscience Videos
          ·April 4, 2017·4 min read

          SuperAger Brains Shrink More Slowly Than Peers’ Brains

          Typical agers lose brain volume twice as fast as SuperAgers, a new study reports.
          Read More
          FeaturedGeneticsOpen Neuroscience Articles
          ·July 18, 2017·5 min read

          A Genetic Influence on Aging Into the 90s, But Not Beyond

          A new study challenges previous research into the role of the FOXO3 gene in super-aging. Researchers found the gene did, to a degree, play a role in longevity, but did not affect living to ages 96+ in men or 100+ in women.
          Read More
          Image shows two old friends.
          FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology
          ·November 2, 2017·4 min read

          Close Friends Linked to a Sharper Memory

          A new PLOS ONE study reports superagers who maintain positive friendships have better cognitive ability and slower memory decline that peers who do not maintain strong social networks.
          Read More
          birthday candles
          FeaturedNeuroscience
          ·July 1, 2018·3 min read

          The Odds of Living to 110 Plus Level Out Once You Hit 105

          Researchers report death rates slow after the age of 105. The study reveals there appears to be no fixed limit to the human life span yet in sight.
          Read More
          an old person
          FeaturedGeneticsNeurologyNeurosciencePsychology
          ·January 4, 2019·13 min read

          The Mysteries of the Super-Ager Revealed

          Scientific research is helping to unlock the secrets behind why some people live to become super-agers. Researchers propose ways in which we can slow the aging process and extend our life spans.
          Read More
          This shows an older lady
          FeaturedNeurologyNeuroscience
          ·September 9, 2019·3 min read

          ‘Superagers’ over 80 have the memory and brain connectivity of twenty-somethings

          Both the default mode network and salience network in superagers had stronger connectivity than typical older adults and similar connectivity as younger adults. Superagers performed similarly to young adults and better than typical older adults in recognition and episodic memory tasks.
          Read More
          This shows a happy older lady
          FeaturedNeuroscienceOpen Neuroscience Articles
          ·May 5, 2020·3 min read

          People aged 95 and over show stronger brain connectivity

          Superagers, people aged 95 and older, showed more activation between their left and right frontoparietal control network in their brains than their younger counterparts. The superior connectivity contributed to better performance on visuospatial cognitive tasks, a new study reports.
          Read More
          This shows a smiling older lady
          FeaturedNeurologyNeuroscience
          ·February 17, 2021·4 min read

          SuperAger Brains Resist Protein Tangles That Lead to Alzheimer’s

          SuperAgers who maintain their cognitive abilities have resistance to the development of Alzheimer's related tau tangles. The resistance to tangles may help to preserve memory.
          Read More
          This shows an old lady
          FeaturedGeneticsNeuroscienceOpen Neuroscience Articles
          ·May 4, 2021·5 min read

          Do People Aged 105 and Over Live Longer Because They Have More Efficient DNA Repair?

          Study reveals people who live to be 105 or older have unique genetic signatures that are linked to more efficient DNA repair.
          Read More
          This shows an older gentleman
          FeaturedNeuroscience
          ·July 1, 2021·5 min read

          How Long Can a Person Live? The 21st Century May See a Record-Breaker

          Extreme longevity will continue to rise over the 21st Century. Researchers estimate a lifespan of between 125 to 130 years will be possible.
          Read More
          This shows an older gentleman
          FeaturedNeuroscience
          ·July 6, 2021·6 min read

          Study Reveals Source of Remarkable Memory of “Superagers”

          The structure of SuperAgers' brains and the connectivity of their neural networks more closely resembles the brains of younger adults, a neuroimaging study reveals.
          Read More
          This shows an older man
          FeaturedNeuroscience
          ·September 30, 2022·4 min read

          Superager Brains Contain ‘Super Neurons’

          Neurons in the memory-associated entorhinal cortex of super-agers are significantly larger than their cognitively average peers, those with MCI, and even in people up to 30 years younger. Additionally, these neurons contained no signs of Tau, a hallmark of Alzheimer's disease.
          Read More
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          • How Severe Illness During Pregnancy Alters Fetal Brain Development
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          • Youth Protein TIMP2 Restores Immune Function in the Aging Brain
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          A 3D digital rendering showing a developing fetal brain connected by glowing neural pathways and floating DNA strands, surrounded by subtle immune cells.

          How Severe Illness During Pregnancy Alters Fetal Brain Development

          A 3D digital illustration of a human brain side-by-side comparison, highlighting the language centers glowing brightly and equally in both a younger and older brain, while executive function areas are dimmed in the older brain.

          Aging Brains Maintain Robust Language Networks Despite Cognitive Decline

          Rejuvenation of Microglia by Youth Protein TIMP2 in the Aging Brain

          Youth Protein TIMP2 Restores Immune Function in the Aging Brain

          A multi-panel documentary photo. Left: A Black man sits alone on a locker room bench with his head down. Center: A Latino man sits withdrawn at a family kitchen table. Right: A White man looks thoughtfully at wellness pamphlets in a public waiting area. All convey isolation.

          Shame, Stigma, and Culture Prevent Male Domestic Violence Survivors From Seeking Help

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