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SuperAgers

·May 24, 2023·4 min read

Alzheimer’s Pathology Found in Superagers With Superior Cognition

A new study found people who are 90+ and have superior cognitive skills have similar levels of brain pathology as Alzheimer's patients. However, they also have less brain pathology of other neurodegenerative diseases. The researchers are now looking at how lifestyle habits and health conditions are associated with superior cognition in individuals who are 90+.

Featured Neuroscience

·March 31, 2023·5 min read

Centenarians Possess Unique Immunity That Helps Them Achieve Exceptional Longevity

Centenarians harbor a unique immune cell type, immune activity, and highly functioning immune system that has adapted to a history of illness, allowing for exceptional longevity.

Featured Genetics Neuroscience

·November 18, 2022·3 min read

What Underpins Exceptional Longevity?

A new study will investigate the genetic and biological mysteries of extreme longevity and healthy aging.

Featured Neuroscience

·September 30, 2022·4 min read

Superager Brains Contain ‘Super Neurons’

Neurons in the memory-associated entorhinal cortex of super-agers are significantly larger than their cognitively average peers, those with MCI, and even in people up to 30 years younger. Additionally, these neurons contained no signs of Tau, a hallmark of Alzheimer's disease.

Featured Neuroscience

·July 6, 2021·6 min read

Study Reveals Source of Remarkable Memory of “Superagers”

The structure of SuperAgers' brains and the connectivity of their neural networks more closely resembles the brains of younger adults, a neuroimaging study reveals.

Featured Neuroscience

·July 1, 2021·5 min read

How Long Can a Person Live? The 21st Century May See a Record-Breaker

Extreme longevity will continue to rise over the 21st Century. Researchers estimate a lifespan of between 125 to 130 years will be possible.

Featured Genetics Neuroscience Open Neuroscience Articles

·May 4, 2021·5 min read

Do People Aged 105 and Over Live Longer Because They Have More Efficient DNA Repair?

Study reveals people who live to be 105 or older have unique genetic signatures that are linked to more efficient DNA repair.

Featured Neurology Neuroscience

·February 17, 2021·4 min read

SuperAger Brains Resist Protein Tangles That Lead to Alzheimer’s

SuperAgers who maintain their cognitive abilities have resistance to the development of Alzheimer's related tau tangles. The resistance to tangles may help to preserve memory.

Featured Neuroscience Open Neuroscience Articles

·May 5, 2020·3 min read

People aged 95 and over show stronger brain connectivity

Superagers, people aged 95 and older, showed more activation between their left and right frontoparietal control network in their brains than their younger counterparts. The superior connectivity contributed to better performance on visuospatial cognitive tasks, a new study reports.

Featured Neurology Neuroscience

·September 9, 2019·3 min read

‘Superagers’ over 80 have the memory and brain connectivity of twenty-somethings

Both the default mode network and salience network in superagers had stronger connectivity than typical older adults and similar connectivity as younger adults. Superagers performed similarly to young adults and better than typical older adults in recognition and episodic memory tasks.

Featured Genetics Neurology Neuroscience Psychology

·January 4, 2019·13 min read

The Mysteries of the Super-Ager Revealed

Scientific research is helping to unlock the secrets behind why some people live to become super-agers. Researchers propose ways in which we can slow the aging process and extend our life spans.