According to researchers, genes within the striatum could be deeply involved in bipolar disorder.
MIT researchers report mothers who contract severe infections during pregnancy face higher autism risks in their children. However, ASD risks could be reduced by blocking the function of certain strains of bacteria found in the mother's gut.
Only 45% of patients with major depressive disorder find benefit from cognitive behavioral therapy (CBT). A neuroimaging study reveals those who respond to CBT have greater neural activity in the right striatum and right amygdala pretreatment than those who find little benefit from the treatment. The findings could serve as a biomarker to discover who will respond to CBT.
Researchers report the striatum and amygdala are less able to track changes in threat levels in those with severe PTSD. The findings may serve as a biomarker to evaluate who may be at greater risk of PTSD symptoms.
Findings could have major implications for future studies into motivation, addiction and decision making, researchers report.
Findings could have implications for treating psychiatric disorders that feature impaired decision making.
Researchers report they have mapped a portion of a mouse brain that could help explain which circuit disruptions may occur in Autism and Huntington's disease.
Researchers implanted a genetic mutation that encodes the DAT protein from a child with ASD into mice. The mice began to exhibit autism-like behavioral deficits. Mice with the DAT T356M mutation had reduced social interaction and a loss in social dominance. The mice also demonstrated an increase in hyperactivity. At the physiological level, the researchers found impaired striatal dopamine transmission and clearance.
Those who find it hard to cope with uncertainty over possible future threats could have an unusually large striatum, a new study reports.