Brain CancerFeaturedGeneticsNeuroscience·May 11, 2022·4 min readKey Protein Identified for Brain Stem Cell LongevityINSR, a protein essential for insulin activity, plays a critical role in stem cell longevity. Additionally, inactivating INSR in glioblastoma brain cancer stem cells inhibits the growth of primitive tumor forming cells.Read More
Auditory NeuroscienceFeaturedGeneticsNeuroscience·May 5, 2022·4 min readNew Tool to Create Hearing Cells Lost in AgingResearchers have identified a master gene that programs ear hair cells into either inner or outer cells. The discovery could lead to new treatments to restore hearing loss associated with aging, noise exposure, or as an adverse reaction to medical therapies.Read More
FeaturedGeneticsNeuroscience·April 6, 2022·5 min readWhat Makes Brain Cells Develop in a Specific Order?Study identified a complete series of ten factors that regulate the development of neurons in a fly's visual system, shedding light on the order in which these neurons develop.Read More
Auditory NeuroscienceFeaturedNeuroscience·March 29, 2022·6 min readReversing Hearing Loss With Regenerative TherapyA new regenerative therapy uses small molecules to program progenitor cells derived from stem cells in the inner ear to grow new hair cells within the cochlear and restore hearing.Read More
FeaturedNeurologyNeuroscience·February 20, 2022·3 min readCough Suppressant Knocks Some Hearts Back Into RhythmResearchers report some over-the-counter cough suppressants can help correct heart rhythm problems in patients with QT syndrome.Read More
FeaturedGeneticsNeurosciencePsychology·January 10, 2022·5 min readNeurons Derived From Stem Cells Predict Psychosis and Cognitive Deficits in Individuals With SchizophreniaClinical symptoms of schizophrenia, such as psychosis and cognitive deficits, can be predicted from the activity of neurons derived from a patient's stem cells.Read More
FeaturedNeuroscience·November 21, 2021·3 min readNew Mothers Could Help Protect Other Babies’ BrainsStem cells collected from the placentas of women who gave birth to healthy babies could reduce neuroinflammation and reduce brain injury in growth-restricted babies.Read More
FeaturedNeurologyNeuroscience·October 11, 2021·3 min readWater Pill May Be Viable to Test as Alzheimer’s TreatmentBumetanide, an FDA-approved potent diuretic used to treat fluid retention caused by heart, kidney, and liver disease may lower the risk of developing Alzheimer's disease for those with a genetic predisposition.Read More
FeaturedGeneticsNeuroscience·October 9, 2021·4 min readWhat Makes Us Human? The Answer May Be Found in Overlooked DNAThe answer to what makes the human brain unique may lie in junk DNA.Read More
FeaturedNeurologyNeuroscience·October 5, 2021·4 min readStudy Detects Origins of Huntington’s Disease in Two-Week-Old Human EmbryosSynthesizing a human embryo from stem cells and using gene editing to insert the Huntingtin gene, researchers found the mutation affected the size of germ layers compared to the control embryos. Findings suggest Huntington's disease may be a neurodevelopmental disorder that presents as a neurodegenerative disease laterRead More
FeaturedGeneticsNeurologyOpen Neuroscience Articles·September 15, 2021·3 min readStem Cells Model Genetic Risk for Developing Alzheimer’s DiseaseStem cell study reveals astrocytes carrying the Alzheimer's associated APOE4 gene release more cholesterol than those carrying the APOE3 gene. Findings shed light on how different versions of the APOE gene in astrocytes influence amyloid-beta production and how the oversupply of cholesterol associated with APOE4 astrocytes may promote amyloid-beta formation in Alzheimer's patients.Read More
FeaturedNeurologyNeuroscience·September 1, 2021·5 min readNew Brain Model Provides Patient-Specific Alzheimer’s Insights and Predictions of Cognitive DeclineA newly developed brain model from cultivated stem cells allowed researchers to analyze molecular pathways of neurons in a dish. Researchers identified specific forms of amyloid beta and tau associated with cognitive decline and Alzheimer's. They also uncovered signaling pathways that influence the production of the toxic proteins.Read More
