Researchers explain how SSRI antidepressants initiate action by targeting a specific type of nerve cells. Findings may lead to the development of faster acting antidepressants.
Antidepressants, such as the SSRI amitriptyline, antibiotics associated with developmental problems and sun cream components are contaminating water, and are being accumulated in fish. Exposure to the medications has effects on the molecular level to the fish. Researchers say this poses a problem as consumption of gilt-head bream is on the rise, and there could be a risk of the contaminants reaching humans via diet.
Researchers explain how a molecular amplification system helps a new class of antidepressants alter brain signaling in specific neurons and how this produces the antidepressant effect.
A new study links antidepressant use during pregnancy with birth defects.
A new study adds to the growing body of research linking inflammation to depression. Researchers found the molecule histamine directly inhibits the release of serotonin in the brain by attaching to inhibitory receptors on serotonin neurons in mice.
Fluoxetine rearranges nerve fibers in the hippocampus of mice, a new study reports.
Chronic stress can affect a person's health and mental well being. Due to the COVID-19 virus, chronic stress is on the rise worldwide. Researchers examine the general and psychological health implications of chronic stress and suggest some methods we can adopt to keep our stress levels in check.
Typically, many people associate depression with feelings of sadness or despair. However, depression can also affect your cognitive abilities and memory. A new paper reviews the impact depression has on cognitive function and considers therapy options to help improve these often overlooked symptoms of the disorder.
Researchers have mapped out a serotonin-driven anxiety circuit that may explain the side effects of anxiety and fear experienced by some patients taking SSRIs.
Serotonin and SSRIs like Prozac can have a major effect on gut bacteria. When exposed to serotonin, specific gut bacteria grew to higher levels. However, when exposed to SSRIs, the bacterium grew to much lower levels in mouse models.
Researchers shed new light on why some people may not respond to antidepressants for major depressive disorder. The study reports, neurons in the brains of some with MDD may become hyperactive in the presence of SSRIs.
According to a new study, pregnant women who take SSRI antidepressants have lower risks of certain pregnancy complications. However, there is an increased risk of neonatal problems associated with mothers who take the medications.