Researchers implanted specialized neural stem cell grafts directly into mice with spinal cord injuries. As the grafts grew, they integrated with and mimicked the animal's existing neural network.
Spinal cord injuries cause stem cells in the bone marrow to rapidly divide. Following the cell division, the stem cells become trapped in the bone marrow.
LIN28, a molecule that regulates cell growth could help in the treatment of spinal cord injury and optic nerve damage. When expressed above normal levels, the molecule fuels axon growth in mice with injury, enabling the body to repair damaged nerves.
Researchers were able to restore the sense of touch to a 28-year-old who suffered a spinal cord injury with the help of new brain-computer interface technology.
People who experience a spinal cord injury have an increased risk of developing a mental health disorder, a new study reports. Those with SCI had higher instances of anxiety, depression, and psychological multimorbidity than those who had not experienced a debilitating injury.
Administering nimodipine to mouse models of spinal cord injury reduced spasticity in the animals.
Mouse models of corticospinal injuries reveal adult neurons begin a natural regeneration process by reverting back to an embryonic state. The regeneration is sustained with the help of a gene more commonly associated with Huntington's disease.
Enhancing mitochondrial transportation and cellular energetics could help promote regeneration and function following spinal cord injury.
Microglia can interfere with macrophages, preventing the movement of these blood immune cells to injury sites. The findings could help in the development of new treatments for multiple sclerosis, Alzheimer's disease, and spinal cord injury.
Researchers have developed a new method for delivering neural precursor cells into rat models of spinal cord injury. The method is safe, effective, and reduces the likelihood of further spinal trauma while delivering larger doses of reparative stem cells. The new approach could also be used for the treatment of ALS and multiple sclerosis.