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SOD1

Featured Genetics Neurology

·April 16, 2018·5 min read

Large Aggregates of ALS Causing Protein Might Help Brain Cells

Researchers report the formation of larger, more visible SOD1 aggregates may help to protect brain cells.

Featured Genetics Neurology Open Neuroscience Articles

·April 18, 2018·4 min read

ALS Treatment Delays Disease and Extends Life: Mouse Study

Researchers report transplanting altered neural stem cells into the brains of mice genetically engineered to exhibit symptoms of ALS, delayed the progression of the disease and extended lifespan.

Electrophysiology Featured Genetics Neurology Open Neuroscience Articles

·June 22, 2018·3 min read

New Technique Helps Uncover Changes in ALS Neurons

A new method reveals some ALS affected neurons display hypo-excitability. Researchers say these changes most likely represent early steps in the disease progression.

Featured Neurology Neuroscience

·October 19, 2018·5 min read

Regulating Microglial Activity May Reduce Inflammation in Neurodegenerative Diseases

Researchers report activating microglia may help reduce the imbalance between neuroprotection and neurotoxicity for neurodegenerative diseases.

Featured Neurology

·February 20, 2019·6 min read

Can a Nerve Injury Trigger ALS?

A new study reveals peripheral nerve damage may trigger the onset and spread of ALS in mouse models of the neurodegenerative disease.

Featured Neurology Neuroscience

·June 17, 2019·4 min read

Antioxidant puts up fight, but loses battle against protein linked to Alzheimer’s disease

During early Alzheimer's disease, SOD1 initially weakens levels of Tau protein. However, as the disease progresses, the antioxidant becomes less effective at protecting the brain against neurodegeneration.

Featured Neurology Neuroscience

·July 22, 2019·5 min read

Gut microbes may affect the course of ALS

Researchers have isolated a molecule that may be under-produced in the gut of those with ALS. Using mouse models of the disease, researchers identified 11 microbial strains that became altered as the disease progressed, or before the development of symptoms.

Featured Neurology Neuroscience Open Neuroscience Articles

·September 17, 2019·4 min read

Environmental toxin produced by algae may lead to ALS

Exposure to the environmental toxin BMAA may elevate the risk of ALS. BMAA is produced by cyanobacteria, a blue-green alga that commonly occurs in marine ecosystems and accumulates in shellfish, sharks, and other sea-life. Those most reliant on sea-foods for their food source may be most at risk.

Featured Genetics Neurology Neuroscience

·March 27, 2020·6 min read

Gene that first slows, then accelerates, progression of ALS in mice identified

The TBK1 gene regulates the disease progression of ALS in mouse models of the neurodegenerative disease. Loss of the TBK1 gene in motor neurons increases SOD1 aggregation and accelerates the onset of the disease.

Featured Genetics Neurology Neuroscience

·April 20, 2020·5 min read

Researchers delay onset of ALS

Increasing the activity of interneurons in later 5 of the primary motor cortex in mouse models of ALS effectively slowed the onset of the disease.

Featured Neurology Open Neuroscience Articles

·August 12, 2020·4 min read

Researchers Utilize Human-On-A-Chip Approach to Model ALS Pathology

Human-on-a-chip technology could provide a more valuable clinical-based model for ALS.

Featured Neurology Open Neuroscience Articles

·September 3, 2020·4 min read

Promising New ALS Drug Candidates

Ebselen, a Selenium-based drug molecule, and several other novel compounds can change the characteristics of SOD1. The findings could help with the development of new therapeutics for ALS.

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SOD1

Large Aggregates of ALS Causing Protein Might Help Brain Cells

ALS Treatment Delays Disease and Extends Life: Mouse Study

New Technique Helps Uncover Changes in ALS Neurons

Regulating Microglial Activity May Reduce Inflammation in Neurodegenerative Diseases

Can a Nerve Injury Trigger ALS?

Antioxidant puts up fight, but loses battle against protein linked to Alzheimer’s disease

Gut microbes may affect the course of ALS

Environmental toxin produced by algae may lead to ALS

Gene that first slows, then accelerates, progression of ALS in mice identified

Researchers delay onset of ALS

Researchers Utilize Human-On-A-Chip Approach to Model ALS Pathology

Promising New ALS Drug Candidates

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Childhood IQ and Wealth: Uncovering Diverse Financial Paths in Adulthood

Stressed Brains Amplify Comfort Food Cravings

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