SHANK3

Random

SHANK3

·January 1, 2020·7 min read

Study may explain how infections reduce autism symptoms

Immune molecules produced during infection influence the social behaviors of mouse models of autism spectrum disorder. The findings may shed light on why some children on the autism spectrum experience a temporary reduction in behavioral symptoms when they have a fever.

Autism Featured Genetics Neuroscience Videos Open Neuroscience Articles Psychology

·May 10, 2016·5 min read

Mouse Model of Autism Offers Insights For Human Patients

Researchers have developed a new mouse model of a genetically linked type of autism. The new model helps reveal more about the role of genes and brain changes associated with the disorder.

Autism Featured Genetics

·August 18, 2017·3 min read

CRISPR Advances Autism Research

Using CRISPR gene editing technology, researchers target the Shank3 gene in monkey embryos. Research backs previous findings of the importance of the Shank3 gene for brain development and its role in autism.

Autism Featured Genetics

·February 18, 2016·5 min read

Researchers Reverse Autism Symptoms

Researchers demonstrate they can reverse some autism symptoms in mice by turning the Shank3 gene on later in life, allowing the brain to correctly rewire itself.

Autism Featured Genetics Neuroscience Open Neuroscience Articles

·April 27, 2020·5 min read

Lithium may treat behavior linked to autism gene

Findings support the idea that lithium, a drug more commonly associated with the treatment of bipolar disorder, may help treat those with SHANK3 related autism.

This shows synapses images as part of this study

Featured Genetics Neuroscience Open Neuroscience Articles

·September 29, 2019·5 min read

Technique can image individual proteins within synapses

A new rapid imaging technique allows researchers to view synaptic proteins at high resolution.

Autism Featured Genetics Neuroscience

·February 28, 2022·6 min read

Familiar Objects Can Prevent Autism-Like Behaviors in Mouse Model

Exposing mice with the autism-associated SHANK3 genetic mutation to new environments can trigger autism-like behaviors, including repetitive movements and problems with social engagement. However, adding familiar objects to the novel environment during the first exposure can reduce the behavioral and brain signaling deficits.

Image shows the word Shank3 and models of molecules.

Autism Featured Genetics Psychology

·December 10, 2015·6 min read

One Gene Plays Role in Autism and Schizophrenia

A new study reports on the role Shank3 plays in both schizophrenia and autism.

Autism Featured Neuroscience Open Neuroscience Articles

·November 9, 2018·4 min read

Autism Associated with Zinc Deficiency in Early Development

A new study reveals a mechanistic link between zinc levels in fetal development, genes and abnormal neural connections associated with autism.

Autism Featured Genetics

·September 1, 2016·5 min read

Zinc May Help Reverse Brain Changes in Autism

According to researchers, cellular changes in the brain caused by genetic mutations associated with Autism can be reversed with the help of zinc.

Auditory Neuroscience Autism Featured Genetics Neuroscience Visual Neuroscience

·March 2, 2020·5 min read

Why those on the autism spectrum are often hypersensitive to light and noise

Mice lacking the autism-associated SHANK3 gene were more sensitive to sensation, including touch. The mice also had overactive excitatory neurons in the somatosensory cortex, which may account for sensory hypersensitivity.

Autism Featured Genetics Neuroscience

·May 24, 2022·5 min read

Mechanism Shared by Mutations in Different Genes Associated With Autism, Schizophrenia, and Other Conditions Discovered

Researchers have identified a mechanism shared by mutations in the SHANK3 and ADNP genes. The genes have been associated with the development of ASD and schizophrenia.

1 2 3