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Scripps Research Institute

·November 18, 2022·5 min read

Can Pharmacotherapies Prevent Alcohol Use Disorder in People With PTSD?

Those with PTSD are almost twice as likely to develop alcohol use disorder than their peers who have not experienced trauma. Researchers report drugs that block FKBP5, such as benztropine, a drug used to control symptoms of Parkinson's disease, and the experimental compound SAFit2 reduce alcohol preference and drinking in models of PTSD.

This shows neurons. The caption best describes the image

Featured Genetics Neurology Open Neuroscience Articles

·March 6, 2021·4 min read

Huntington’s Disease Driven by Slowed Protein-Building Machinery in Cells

The mutated huntingtin protein slows ribosome movement and decreases protein synthesis.

Autism Featured Genetics Neuroscience Open Neuroscience Articles

·April 15, 2020·5 min read

Autism in males linked to defect in brain immune cells and microglia

An over-production of eIF4E impairs microglial cells, hampering their ability to effectively prune synapses and leading to autism-like behaviors in male mouse models of ASD.

Featured Genetics Neuroscience

·July 28, 2022·5 min read

New “Origins of Life” Chemical Reactions Discovered

Researchers discovered a new set of chemical reactions that use cyanide, ammonia, and carbon dioxide generates amino acids and nucleic acids, the building blocks of proteins and DNA.

Featured Neuroscience

·June 26, 2018·6 min read

A New Way to Block Alcohol Addiction and Ease Withdrawal Discovered

Activating a receptor found in neurons in the habenula could help treat alcohol addiction and ease withdrawal symptoms, researchers report.

Image shows a hand holding a DNA double helix.

Featured Genetics

·January 25, 2017·6 min read

Scientists Create First Stable Semisynthetic Organism

Researchers report they have developed the first stable synthetic organism that holds a pair of synthetic bases in its genetic code.

Featured Neuroscience Psychology

·July 26, 2023·7 min read

Glutamate Receptor Activation: A Potential Cure for Opioid Addiction?

Scientists discovered a potential new weapon in the battle against opioid use disorder (OUD), a condition that affects over two million people in the U.S. alone. The drug, ADX106772, acts on metabotropic glutamate 2 receptors in the brain, leading to a reduction in oxycodone intake and drug-seeking behavior in an animal model.

Featured Neuroscience Psychology

·April 28, 2023·5 min read

Insomnia Drug Belsomra May Help Treat Opioid Addiction

A preclinical study found that suvorexant (Belsomra), an insomnia drug, could be a potential treatment for opioid use disorder (OUD) in rats. If the results are replicated in humans, the drug could offer a promising treatment for the millions of people with OUD and reduce drug intake and block relapse.

Featured Neurology Neuroscience

·June 12, 2023·6 min read

Alcohol in Excess Hastens Alzheimer’s Progression

Repeated alcohol intoxication can speed up Alzheimer’s disease progression associated with a genetic predisposition. The research demonstrated that mice exposed to consistent alcohol intoxication showed cognitive decline about two months earlier than typically expected.