A new study reports reduced levels of Rheb result in memory loss in animal models of dementia.
Researchers have identified a biochemical cascade that leads to the destruction of synapses in the brain. The findings open new avenues of research into the treatment of Alzheimer's disease.
Study reveals up to 45% of people infected with COVID-19 were asymptomatic. The findings suggest asymptomatic infections likely played a significant role in the early and ongoing spread of coronavirus.
Structural mapping of both SARS and SARS-CoV-2, the virus that causes COVID-19, reveals an almost identical site on both coronaviruses to which the CR3022 antibody binds. This suggests a functionally important and vulnerable site for this family of coronaviruses.
PPL2 neurons help modulate the strength of memories.
Levels of a key molecule are elevated in the amygdala of both humans and mouse models of PTSD. The microRNA, mir-135b-5p, may be a novel biomarker for treating the disorder.
A new study reveals some experimental antibody treatments for neurodegenerative disorders increase neuroinflammation. The effect was seen in human microglia, not mouse microglia. This may explain why mouse studies have shown these treatments to be effective, but the effect has not been replicated in human studies.
Mutations in PTEN affect the assembly of connections between two brain areas important for the processing of social cues, researchers report.
The severity of Charcot-Marie-Tooth disease is linked to the degree to which the aminoacyl-tRNA synthetases enzyme is relaxed or extended.
Study reveals how two neural circuits dictate the choice between social approach and avoidance. The network connecting the infralimbic cortex to the basolateral amygdala (BLA) impairs social behavior if there is a decrease in neural activity. Another network connecting the prelimbic cortex to the BLA similarly impairs social behavior if the neural activity is increased.
An immune protein called CSF1 may contribute to feelings of anxiety as a result of alcohol withdrawal for those with alcohol use disorder.
A new advanced imaging technique shows how cholesterol regulates the production of Alzheimer's associated amyloid beta proteins in astrocytes.
