Scripps Research Institute

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Scripps Research Institute

·March 6, 2023·5 min read

How Heavy Alcohol Consumption Increases Brain Inflammation

The immune signaling molecule interleukin 1B (IL-1B) is present at higher levels in mouse models of alcohol use disorder. The IL 1B pathway plays a different role in animal models of AUD, causing inflammation in brain areas that play a critical role in decision-making.

This shows neurons. The caption best describes the image

Featured Genetics Neurology Open Neuroscience Articles

·March 6, 2021·4 min read

Huntington’s Disease Driven by Slowed Protein-Building Machinery in Cells

The mutated huntingtin protein slows ribosome movement and decreases protein synthesis.

Featured Neuroscience Open Neuroscience Articles

·June 8, 2022·5 min read

Immune Protein May Drive Alcoholism Relapse

An immune protein called CSF1 may contribute to feelings of anxiety as a result of alcohol withdrawal for those with alcohol use disorder.

Featured Genetics Neuroscience

·January 13, 2020·2 min read

Long-term memory performance depends upon gating system

Fruit fly study reveals suppression of a genetic switch boosts long-term memory.

Featured Genetics Neuroscience Open Neuroscience Articles

·July 13, 2021·4 min read

Long-Term Memory Setup Requires a Reliable Delivery Crew

Research shows the role the molecular hauler KIF5C plays in long-term memory and synaptic plasticity.

Featured Genetics Neuroscience

·April 16, 2021·3 min read

Neural Plasticity Depends On This Long Noncoding RNA’s Journey From Nucleus to Synapse

Study sheds new light on the role noncoded RNAs play at the synapse.

Electrophysiology Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·January 12, 2020·4 min read

Neurons’ energy organelle protected from damage linked to ALS & Alzheimer’s

Researchers have identified a set of drug-like compounds, including a common ingredient in throat lozenges, that can help protect mitochondria from the stresses associated with neurodegenerative diseases.

Featured Genetics Neuroscience

·July 28, 2022·5 min read

New “Origins of Life” Chemical Reactions Discovered

Researchers discovered a new set of chemical reactions that use cyanide, ammonia, and carbon dioxide generates amino acids and nucleic acids, the building blocks of proteins and DNA.

Featured Genetics Neurology Open Neuroscience Articles

·September 16, 2020·4 min read

New Gene Implicated in ALS and Other Motor Neuron Diseases

A defective protein quality control system leads to motor neuron death associated with disorders like ALS.

Featured Neuroscience Psychology

·March 31, 2021·4 min read

Newly Discovered Node in Brain Could Expand Understanding of Dysfunctional Social Behavior

Researchers have identified a specific node in the brain of mice that regulates vocalizations in response to social situations. If a similar location could be found in the human brain, researchers say it could potentially lead to new insight into social dysfunctions associated with autism and depression.

Image shows the chemical structure of KOR

Featured Neurology Pain

·December 4, 2016·4 min read

Novel Compound to Alleviate Pain and Itch Identified

A new study identifies a possible candidate to help alleviate pain and itch sensations.

Featured Genetics Neuroscience Psychology

·June 19, 2019·4 min read

Overcoming PTSD: Study reveals memory disruption drug target

Levels of a key molecule are elevated in the amygdala of both humans and mouse models of PTSD. The microRNA, mir-135b-5p, may be a novel biomarker for treating the disorder.

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