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Scripps Research Institute

·April 4, 2020·4 min read

Clues to COVID-19 coronavirus’s vulnerability emerge from an antibody against SARS

Structural mapping of both SARS and SARS-CoV-2, the virus that causes COVID-19, reveals an almost identical site on both coronaviruses to which the CR3022 antibody binds. This suggests a functionally important and vulnerable site for this family of coronaviruses.

Featured Neurology Neuroscience

·February 1, 2022·4 min read

Compound in the Herb Rosemary May Be Useful Against COVID-19 and Other Inflammatory Diseases

Carnosic acid, a compound found in the herb rosemary, can block the interaction with the COVID-19 SARS_CoV_2 spike protein and ACE2, the protein receptor the virus uses to gain access into cells. The compound appears to have anti-inflammatory effects and has previously been associated with a reduction in Alzheimer's symptoms.

Image shows a brain surrounded by electricity.

Featured Neuroscience

·February 1, 2017·5 min read

Deep Brain Stimulation Blocks Heroin Relapse: Rat Study

According to researchers, deep brain stimulation reduces the desire to use heroin and rat models of addiction.

Featured Neurology Neuroscience

·December 14, 2022·6 min read

Discovery Could Explain Why Women Are More Likely to Get Alzheimer’s

Complement C3, a chemically modified form of an inflammatory immune protein, was more abundant in post mortem brain tissue of women who died from Alzheimer's disease than in males.

Featured Neuroscience Open Neuroscience Articles

·October 17, 2018·5 min read

Engineered Enzyme Eliminates Nicotine Addiction in Preclinical Tests

Researchers have engineered a new enzyme that breaks down nicotine in the bloodstream before it reaches the brain. The treatment reduces the urge to smoke and reverses signs of nicotine dependence, preventing relapse.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·July 22, 2019·4 min read

Exosomes may hold the answer to treating and diagnosing developmental brain disorders

Exosomes carry signaling information required to regulate neural circuit development.

Featured Neurology Neuroscience

·March 29, 2021·4 min read

Experimental Antibodies for Parkinson’s and Alzheimer’s May Cause Harmful Inflammation

A new study reveals some experimental antibody treatments for neurodegenerative disorders increase neuroinflammation. The effect was seen in human microglia, not mouse microglia. This may explain why mouse studies have shown these treatments to be effective, but the effect has not been replicated in human studies.

This shows a finger touching an image of a brain

Featured Neuroscience

·February 4, 2021·4 min read

Experimental Vaccine Blunts the Deadliest of Synthetic Opioids

A newly developed experimental vaccine can diminish the fatal respiratory effects of carfentanil and fentanyl in rodent models.

Featured Neurology Neuroscience

·March 28, 2020·3 min read

FDA approves ozanimod for treatment of multiple sclerosis

The FDA has approved a new drug named Ozanimod for the treatment of multiple sclerosis. Ozanimod binds to receptors in lymphocytes' surfaces, preventing them from reaching the brain. As the number of active lymphocytes decreases, the attack on the immune system diminishes.

Featured Genetics Neuroscience

·April 26, 2019·4 min read

Gene repair improves memory and seizures in adult autism model

Researchers genetically restored levels of the SynGAP protein in adult mice who were deficient. Restoring the protein levels resulted in improved memory and a reduction in seizures related to the SYNGAP1 disorder, a form of autism. Findings suggest it is possible to extend the window of treatment for those with this specific form of ASD, beyond infancy and into adulthood.

Featured Genetics Neurology Open Neuroscience Articles

·November 21, 2017·5 min read

Good Cells Gone Bad

Researchers uncover how the SNO reaction may contribute to the onset of Parkinson's disease.

Featured Genetics Neurology Neuroscience

·December 6, 2020·5 min read

Hidden Network of Enzymes Accounts for Loss of Brain Synapses in Alzheimer’s

Researchers have identified a biochemical cascade that leads to the destruction of synapses in the brain. The findings open new avenues of research into the treatment of Alzheimer's disease.

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