Study identifies inflammatory mechanisms and cellular activity in the amygdala that drives alcohol addiction in mice. Chronic alcohol exposure compromises immune cells in the brain, driving anxiety and alcohol consumption that may lead to the development of AUD.
Male and female rodents exhibit distinct symptoms and brain features of both PTSD and alcohol use disorder. Following trauma, males show increased GABA receptor function, while females showed increased GABA release.
The same area of the brain can motivate and suppress a learned behavior at the same time, a new study reports.