Research seeks the 'master knob' to turn on nerve repair. Modulating immune response to injury could accelerate the regeneration of severed peripheral nerves, a new study in an animal model has found. By altering activity of the macrophage cells that respond to injuries, researchers dramatically increased the rate at which nerve processes regrew.
Researchers uncover a key to the development of the peripheral nervous system, providing new hope to patients suffering from hereditary neuropathy.
A Cell Reports study identifies molecules that allow Schwann cells to help regenerate nerves.
Schwann cells are much more prolific in generating myelin than previously believed. Knocking out the fbxw7 gene in mouse models, researchers discovered individual Schwann cells began to spread myelin across many axons.
In a groundbreaking finding, researchers have identified a new sensory organ under the skin that can detect pain as a result of impact or pinpricks. The organ comprises of glial cells with multiple long protrusions which collectively make up the mesh-like organ under the skin.
A preclinical study reports Schwann cells assist injured axons by releasing protective sugars. The findings have positive implications for the treatment of neurodegenerative diseases like ALS.
A new synthetic conduit can bridge large nerve gaps by guiding the regrowth of neurons. When implanted into the arms of macaques with nerve defects in their arms, the conduit boosted neurogenesis and the nerve's ability to conduct signals for a year.
Researchers report a protein normally associated with prion diseases may help to maintain myelin.
Schwann cells help protect nerves against blood clotting factors that cause degeneration, researchers report.