A new study reveals how Schwann cells in the PNS degrade myelin following nerve injury.
Study sheds light on how macrophages use a specific cell signalling pathway to control peripheral nerve repair following damage.
Researchers discover a build up of acylcarnitines in Schwann cells can lead to nerve damage noted in patients with peripheral neuropathy.
Researchers reveal an unexpected cause for hidden hearing loss.
Severed axonal segments signal to Schwann cells to begin actin sphere formation and axon disintegration. If the process is disrupted, axon disintegration is slowed and axon fragments impair nerve regeneration.
A new synthetic conduit can bridge large nerve gaps by guiding the regrowth of neurons. When implanted into the arms of macaques with nerve defects in their arms, the conduit boosted neurogenesis and the nerve's ability to conduct signals for a year.
A preclinical study reports Schwann cells assist injured axons by releasing protective sugars. The findings have positive implications for the treatment of neurodegenerative diseases like ALS.
Researchers report a protein normally associated with prion diseases may help to maintain myelin.
Doctors performed the first-ever FDA approved Schwann cell transplantation in a patient with a new spinal cord injury. The procedure is a Phase 1 clinical trial designed to evaluate the safety and feasibility of transplanting the patient’s own Schwann cells.
Study reports it may be possible to fine tune molecular signals to insure peripheral nerves are correctly insulated and function properly.
Researchers uncover a key to the development of the peripheral nervous system, providing new hope to patients suffering from hereditary neuropathy.
Researchers from the University of Plymouth have discovered the tole PrPC plays in the development of neurofibromatosis 2 tumors. According to the study, the prion protein is overproduced in schwannomas, compared with healthy Schwann cells. This overproduction is a result of Merlin deficiency and contributed to tumor growth in NF2 patients.
