The researchers knocked out the Erk gene during peripheral nervous system development in mice. The researchers noticed the neurons of these knock-out mice were largely unaffected, but Schwann cells were "just devastated at every stage of development."
Research seeks the 'master knob' to turn on nerve repair. Modulating immune response to injury could accelerate the regeneration of severed peripheral nerves, a new study in an animal model has found. By altering activity of the macrophage cells that respond to injuries, researchers dramatically increased the rate at which nerve processes regrew.
Doctors performed the first-ever FDA approved Schwann cell transplantation in a patient with a new spinal cord injury. The procedure is a Phase 1 clinical trial designed to evaluate the safety and feasibility of transplanting the patient’s own Schwann cells.
Researchers have discovered that, following nerve damage, peripheral glial cells produce the growth factor neuregulin1, which assists in the regeneration of damaged nerves.
Researchers uncover a key to the development of the peripheral nervous system, providing new hope to patients suffering from hereditary neuropathy.
Researchers restore significant bladder function, through nerve regeneration, in rats with severe spinal cord injuries.
A new study reveals how Schwann cells in the PNS degrade myelin following nerve injury.
Researchers report a protein normally associated with prion diseases may help to maintain myelin.