TRPML1 may contribute to the neuroprotective and anti-aging properties of rapamycin.
Researchers have been able to identify and deactivate a brain pathway liked to memories associated with alcohol cravings in rats.
The anti-aging drug Rapamycin only prolongs the lifespan of females according to research using fruit fly and mouse models. Rapamycin increased autophagy in female intestinal cells, but not in males. Findings suggest biological sex may be a crucial factor in the effectiveness of anti-aging drugs.
Brief exposure to Rapamycin, a promising anti-aging drug that has positive effects on health and lifespan, has the same effect as long-term exposure to the drug in animal models. The findings pave the way for testing the effects of short-term rapamycin exposure on the lifespan of humans.
Researchers propose a strategy for repurposing geroprotectors, including rapamycin and metformin, as potential COVID-19 infection prevention methods.
A new study reports the Ketogenic diet can help to improve cognition. The study reports the Ketogenic diet can help improve balance in the gut microbiome, lower blood glucose levels and increase the processes that help to clear amyloid beta from the brain.
Rapamycin, a transplant anti-rejection drug, enhances survival and reduces the disease progression in a mouse model of Leigh's syndrome, a new study reports.
Hyperconnectivity triggered by loss of PTEN gene can be blocked by treatment with rapamycin. New research from Cold Spring Harbor...
According to researchers, lithium, a drug commonly used to treat bipolar disorder, and rapamycin can help to protect neurons from further damage in those with TBI.
Researchers were able to regenerate an astonishing degree of axonal growth at the site of severe spinal cord injury in rats. Results were then replicated using two human stem cell lines, one already in human trials for ALS. “We obtained the exact results using human cells as we had in the rat cells,” said Tuszynski.
Researchers discover a new mechanism of action for rapamycin that could help prevent neurological damage associated with neurodegenerative diseases.
Genetically silencing mTORC2 in mouse models prolonged lifespan, suppressed seizures, increased long-term memory, and reduced autism-like behaviors.
