As novel visual patterns become familiar, stark changes occur in the visual cortex. Gamma rhythms give way to low-wave beta waves, and the neural activity switches from PV neurons in favor of inhibitory SOM neurons.
Reducing the excitation-inhibition ratio by diminishing excitability of pyramidal neurons or increasing excitability of PV neurons led mice to spend more time engaged in social encounters. Researchers believe the excitation-inhibition balance may play a key role in autism and normal social behavior.
Researchers have discovered a link between specific neural circuits to distinct behavioral symptoms of depression. The study, published in Cell, reports altering the networks helped to improve symptoms such as social withdrawal and helplessness.
Researchers report many PV defects could have their origin, not during adult life, but instead in the SST templates that set circuit parameters in the first place.
A new study provides deeper understanding of the mechanisms the brain uses to sync up for conscious thought.
Neuroscientists report that two major classes of brain cells repress neural activity in specific mathematical ways: One type subtracts from overall activation, while the other divides it.