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          psychopharmacology

          This shows a cortical neuron
          FeaturedNeurosciencePsychology
          ·February 16, 2023·3 min read

          Receptor Location Matters for Psychedelic Drug Effects

          Location bias may explain how psychedelic medications work. Researchers found that engaging serotonin 2A receptors inside neurons promotes the growth of new connections, but engaging the same receptor on the outside of a neuron does not. The findings may guide the development of new psychoplastogens to treat a range of disorders including depression and PTSD.
          Read More
          This shows a brain
          AutismFeaturedNeuroscienceOpen Neuroscience Articles
          ·February 14, 2023·4 min read

          Drug Shown to Alleviate Autism-Associated Behavior

          A newly developed drug that blocks sodium channels in the cell membrane that can reverse MYT1L failure alleviates social behavior deficits in mouse models of ASD.
          Read More
          This shows a drawing of a person holding the back in pain
          FeaturedNeurologyNeuroscienceOpen Neuroscience ArticlesPain
          ·February 2, 2023·7 min read

          Antidepressants Use for Chronic Pain on the Rise, but Are They Effective?

          SNRI antidepressants appear to be effective in the treatment of a range of pain conditions including neuropathic pain, fibromyalgia, and postoperative pain. Tricyclic antidepressants may not be effective in the treatment of pain.
          Read More
          This shows a man's fist
          FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology
          ·January 31, 2023·5 min read

          Beta-Blocker Use Associated With Lower Rates of Violence

          Beta-blockers, a class of drugs commonly used to treat hypertension and cardiovascular disorders, appear to reduce aggressive and violent behaviors, and can reduce suicidal behaviors.
          Read More
          This shows a brain
          FeaturedNeurologyNeuroscience
          ·January 31, 2023·4 min read

          Do Sleep Medications Increase Your Chances of Dementia?

          People who frequently take sleeping medications are 79% more likely to develop dementia than those who never use sleeping pills to aid their rest.
          Read More
          This shows a man holding a beer bottle
          FeaturedNeurosciencePsychology
          ·January 30, 2023·4 min read

          Experimental Anti-depression Drug May Also Be Useful in Treating Alcohol Use Disorder

          MAP4343, an experimental antidepressant compound reversed alcohol intake in rat models of alcohol use disorder. The findings pave the way for utilizing the compound for the treatment of AUD in humans.
          Read More
          This shows a man holding his back in pain
          FeaturedNeurosciencePainPsychology
          ·January 30, 2023·5 min read

          How Ketamine Acts as Antidepressant in Chronic Pain

          Chronic pain in mice activates Tiam1 in pyramidal neurons in the anterior cingulate cortex, increasing the number of dendritic spines and inducing synaptic plasticity. Ketamine's antidepressant effect in chronic pain is mediated by the drug blocking Tiam1-dependent maladaptive synaptic plasticity in ACC neurons.
          Read More
          This shows a young man crying
          FeaturedNeurosciencePsychology
          ·January 27, 2023·4 min read

          A Drug That Increases Dopamine Can Reverse the Effects of Inflammation on the Brain in Depression

          Levodopa, a drug commonly prescribed for the treatment of Parkinson's disease that increases dopamine in the brain was found to reverse the effects of neuroinflammation on the reward system and improve symptoms associated with depression.
          Read More
          This shows a depressed man
          FeaturedNeurosciencePsychology
          ·January 23, 2023·5 min read

          Study Explains Emotional ‘Blunting’ Caused by Common Antidepressants

          SSRI antidepressants can make users less sensitive to rewards, resulting in emotional blunting many users experience. The findings provide new evidence for the role serotonin plays in reinforcement learning.
          Read More
          This shows a heart and a brain
          FeaturedNeurologyNeuroscienceOpen Neuroscience Articles
          ·January 18, 2023·4 min read

          How Serotonin Genes and SSRIs Can Contribute to Heart Valve Disease

          Taking SSRIs and having the "long-long" serotonin SERT genetic variant lowers SERT activity in the mitral valve, leading to degenerative mitral regurgitation, one of the most common heart valve diseases.
          Read More
          This shows people in a city park
          FeaturedNeurosciencePsychology
          ·January 17, 2023·5 min read

          Frequent Visits to Green Space Linked to Lower Use of Certain Prescription Meds

          People who frequently visit green spaces are less likely to use prescription medications for anxiety, depression, high blood pressure, and asthma, a new study reports.
          Read More
          This shows different pills
          FeaturedNeurosciencePsychology
          ·January 15, 2023·5 min read

          Old Antipsychotic Drugs May Offer New Option to Treat Type 2 Diabetes

          Diphenylbutylpiperidines (DPBPs), an older class of antipsychotic medications can effectively be repurposed to help treat type 2 diabetes, a new study reports.
          Read More
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          This shows an older couple dancing.

          Jiving into Joy: Dance Sessions Elevate Health and Well-being in 85+ Age Group

          This shows neurons.

          New Insights Into Synaptic Pruning During Brain Development

          This shows a child and money.

          Childhood IQ and Wealth: Uncovering Diverse Financial Paths in Adulthood

          This shows a woman surrounded by junk food.

          Stressed Brains Amplify Comfort Food Cravings

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