People who frequently take sleeping medications are 79% more likely to develop dementia than those who never use sleeping pills to aid their rest.
Beta-blockers, a class of drugs commonly used to treat hypertension and cardiovascular disorders, appear to reduce aggressive and violent behaviors, and can reduce suicidal behaviors.
SNRI antidepressants appear to be effective in the treatment of a range of pain conditions including neuropathic pain, fibromyalgia, and postoperative pain. Tricyclic antidepressants may not be effective in the treatment of pain.
A newly developed drug that blocks sodium channels in the cell membrane that can reverse MYT1L failure alleviates social behavior deficits in mouse models of ASD.
Location bias may explain how psychedelic medications work. Researchers found that engaging serotonin 2A receptors inside neurons promotes the growth of new connections, but engaging the same receptor on the outside of a neuron does not. The findings may guide the development of new psychoplastogens to treat a range of disorders including depression and PTSD.
Vasodilators such as fasudil, commonly used for the treatment of stroke, restored pyramidal neurons in the prefrontal cortex of mouse models of schizophrenia associated with genetics.
Those with cocaine use disorder who were administered ketamine for depression or pain experienced two-to-four times higher remission rate.
Apremilast, an FDA-approved drug for the treatment of skin conditions including psoriasis and psoriatic arthritis, triggers increased activity in the nucleus accumbens, a brain area associated with regulating alcohol intake. Apremilast reduced drinking behaviors in mouse models with a genetic risk of alcohol use disorder.
Prazosin, an FDA-approved medication for the treatment of hypertension may help to prevent relapse in people with cardiovascular and behavioral symptoms of alcohol withdrawal, a new study reports.
Recent studies have explored the use of psychedelics for the treatment of a range of mental health disorders. A new study reveals more insightful and mystical "trips" while exposed to psychedelics may be linked to an enduring reduction of symptoms for those with anxiety and depression.
In addition to helping treat mental health disorders, psychedelic treatments can help people overcome addictions. A new study reports psychedelics can help smokers quit nicotine and remain smoke-free for at least five years.
During the COVID-19 pandemic, there has been an uptick in the use of antidepressant medications to combat symptoms of depression. Researchers discuss the impact of antidepressant usage and provide guidelines for safe and effective withdrawal from antidepressant medications.
