Researchers report alcohol can strengthen fearful memories, but a drug used to treat seizures may reverse the effects.
A new study reports two doses of the psychedelic compound psilocybin reduced heavy alcohol consumption by 83% when combined with therapy for those with alcohol use disorder.
A new research paper outlines principles for testing new treatments for depression and the use of ketamine to help treat the illness.
Findings could help to design new treatments for mood disorders as effective as lithium, but with fewer side effects.
Psychedelics, such as psilocybin, provide lasting improvements in mood and feelings of social connectedness, after the effect of the drug has worn off.
Chronic pain in mice activates Tiam1 in pyramidal neurons in the anterior cingulate cortex, increasing the number of dendritic spines and inducing synaptic plasticity. Ketamine's antidepressant effect in chronic pain is mediated by the drug blocking Tiam1-dependent maladaptive synaptic plasticity in ACC neurons.
The SSRI sertraline (Zoloft), if taken while pregnant, can result in birth defects caused by the drug damaging a cell's genetic information. Researchers report one potential way to counter the effect is with specific antioxidants.