Researchers report alcohol can strengthen fearful memories, but a drug used to treat seizures may reverse the effects.
A new study reports two doses of the psychedelic compound psilocybin reduced heavy alcohol consumption by 83% when combined with therapy for those with alcohol use disorder.
A new research paper outlines principles for testing new treatments for depression and the use of ketamine to help treat the illness.
Researchers identify the mechanisms behind tricyclic antidepressants' ability to help relieve nerve pain.
A new study reports a single dose of ketamine given a week before a stressful even can act as a buffer against PTSD.
Findings could help to design new treatments for mood disorders as effective as lithium, but with fewer side effects.
Psychedelics, such as psilocybin, provide lasting improvements in mood and feelings of social connectedness, after the effect of the drug has worn off.
According to researchers, a century old drug originally developed to treat African sleeping sickness shows promise for treating symptoms of autism.
Chronic pain in mice activates Tiam1 in pyramidal neurons in the anterior cingulate cortex, increasing the number of dendritic spines and inducing synaptic plasticity. Ketamine's antidepressant effect in chronic pain is mediated by the drug blocking Tiam1-dependent maladaptive synaptic plasticity in ACC neurons.
The SSRI sertraline (Zoloft), if taken while pregnant, can result in birth defects caused by the drug damaging a cell's genetic information. Researchers report one potential way to counter the effect is with specific antioxidants.
Placebos can help reduce feelings of guilt, even when the placebo is given openly, a new study reports.
Psilocybin can restore mGluR2 levels in the prefrontal cortex, and this leads to a reduced risk of relapse for those with alcohol use disorder.
