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          psychedelics

          This shows a psychedelic brain
          FeaturedNeurosciencePsychology
          ·March 20, 2023·5 min read

          How DMT Psychedelic Alters Perception of Reality

          The psychedelic compound DMT (Dimethyltryptamine) increases connectivity across the brain, allowing for greater communication between different areas and networks. The brain changes are most prominent in brain areas linked to higher functioning, such as imagination.
          Read More
          Image shows a swirly brain.
          FeaturedMost PopularOpen Neuroscience ArticlesPsychology
          ·August 22, 2016·3 min read

          How LSD Affects Language

          A new study looks at how LSD affects the ability to correctly put a name to an object.
          Read More
          Image of a woman and swirling colors.
          FeaturedOpen Neuroscience ArticlesPsychology
          ·April 13, 2016·5 min read

          How LSD Can Make Us Lose Our Sense of Self

          Increases in global connectivity in brain networks of people under the influence of LSD correlate with the degree to which a person reported a sense of ego dissolution.
          Read More
          horse drawings
          AutismFeaturedNeuroscienceOpen Neuroscience Articles
          ·May 14, 2018·3 min read

          How Our Ancestors with Autistic Traits Led a Revolution in Ice Age Art

          A new study reveals a common autistic trait, the ability to focus on detail, may have allowed realism to flourish in Upper Paleolithic art.
          Read More
          This shows a woman and mushrooms.
          FeaturedNeurosciencePsychology
          ·April 4, 2025·3 min read

          How Psilocybin Lifts Mood Without the Hallucinogenic Trip

          Researchers have uncovered two key brain mechanisms—specific neurons and a serotonin receptor—that help explain how psilocybin produces long-lasting antidepressant effects. Their study identified pyramidal tract neurons in the medial frontal cortex and the serotonin 5-HT2A receptor as essential to the therapeutic action of psilocybin.
          Read More
          This shows the compound structure
          FeaturedNeuroscienceOpen Neuroscience Articles
          ·September 17, 2020·6 min read

          How Psychedelics Bind to Key Serotonin Receptor

          Researchers have uncovered the structure of psychedelic compounds when they actively bind to the 5-HT2A serotonin receptor on the surface of brain cells. The discovery could lead to the exploration of more precise compounds that offer the therapeutic effects of psychedelics for mental health disorders, but without the hallucinations.
          Read More
          This shows a psychedelic brain
          FeaturedNeuroscience
          ·October 24, 2022·4 min read

          How Psychedelics Light Up Brain’s Neuropathways

          Study reveals the basic neurobiology of how psychedelics work at the chemical, molecular, neural, and network levels within the brain.
          Read More
          This shows an illustration of colorful, psychedelic neurons.
          FeaturedNeurosciencePsychology
          ·April 8, 2026·8 min read

          How Science Solved the Mystery of the Psychedelic High

          A massive international study identifies a universal pattern of brain activity across psilocybin, LSD, DMT, and more. Researchers found that all major psychedelics dissolve brain network boundaries, triggering global "cross-talk."
          Read More
          Image shows DMT-responsive receptors.
          FeaturedNeuroscienceOpen Neuroscience Articles
          ·October 9, 2017·3 min read

          Human Minibrains Reveal Effects of Psychedelic Substance

          A new study reveals psychedelic substances may have a neuroprotective role when it comes to inflammation. Researchers also report psychedelics can alter signaling pathways associated with neuroplasticity.
          Read More
          This shows a blurry blue man
          FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology
          ·July 15, 2019·4 min read

          Improved mood and focus reported by microdosers

          Microdosing, a growing trend where people take small doses for psychedelic drugs, is associated with improved mood, focus, and creativity. For some, microdosing may provide a possible alternative to SSRI antidepressants. However, researchers warn of some potential problems with microdosing, including negative side effects, psychological stigma, and exposure to elicit, black market products.
          Read More
          This shows a psychedelic brain.
          FeaturedNeurosciencePsychology
          ·July 28, 2023·5 min read

          Journeys Beyond: Contrasting Psychedelic Trips and Near-Death Experiences

          A research study scrutinizes the parallels and differences between a near-death experience (NDE) during a coma and the experience induced by a potent psychedelic drug, 5-Methoxy-DMT (5MeO-DMT). The researchers found shared themes, such as ego dissolution and space-time transcendence.
          Read More
          This shows brain scans from the study
          FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology
          ·March 16, 2022·3 min read

          Largest Ever Psychedelics Study Maps Changes of Conscious Awareness to Neurotransmitter Systems

          Study reveals how psychedelic drug-induced changes in subjective awareness are rooted in specific neurotransmitter systems.
          Read More
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          This shows a person and abook.

          Reading Fiction Can Rewire Real-World Forgiveness and Empathy

          This shows the outline of a woman and a brain.

          PCOS/PMOS Increases Alzheimer’s Risk

          This shows a person holding a glass of scotch and microglia.

          Alcohol Tricks Brain Cells Into Destroying Themselves

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          Daytime Napping Linked to Higher Risk of Dementia

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