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psychedelics

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Featured Neuroscience Open Neuroscience Articles Psychology

·September 2, 2018·5 min read

Potent Psychedelic DMT Mimics Near Death Experience in the Brain

Researchers report DMT, the psychoactive compound of ayahuasca, can mimic actual near death experiences in healthy subjects.

This shows a man holding a wine glass against a psychedelic backdrop.

Featured Neuroscience

·November 10, 2025·4 min read

Psychedelics Calm Stress Circuits to Reduce Alcohol Drinking

New research shows that psilocin, the active metabolite of the psychedelic psilocybin, may reduce alcohol consumption by calming stress-sensitive neurons in the central amygdala. In female mice exposed to long-term alcohol use, psilocin dampened the hyperactivity of these neurons, temporarily reducing drinking.

This shows a brain overlayed on a person's head with a swirly, psychedelic background

Featured Neuroscience Psychology

·April 4, 2019·5 min read

Psychedelic drug MDMA may reawaken ‘critical period’ in brain to help treat PTSD

MDMA, a psychedelic drug, has successfully been used to reopen the 'critical period' of learning the reward values of social behaviors. Researchers report, in mature mice given MDMA, oxytocin triggers signaling in synapses that help encode social learning and memory, a process that does not usually occur in older animals. The findings could help in the development of treatments for PTSD and other disorders.

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Featured Neuroscience Psychology

·May 21, 2022·5 min read

Psychedelics: How They Act on the Brain to Relieve Depression

Researchers explore the effect psychedelics have on the brain and how they are effective at treating depression.

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·February 28, 2020·3 min read

Overdosing on psychedelics improved mental and physical health: Case studies

A recent case study report highlights the effects of LSD overdoses on three women, revealing the subjects experienced improvements in physical and mental health following their overdoses.

Featured Neuroscience Open Neuroscience Articles Psychology

·February 11, 2019·5 min read

Does Microdosing Improve Mood and Performance?

A new study reports those who microdose psychedelics report improvements in attention and mental health. However, a number of people report an increase in neuroticism following six weeks of microdosing.

Featured Neuroscience Psychology

·October 27, 2025·4 min read

Psychedelics May Rewire Memory Circuits Key to Mental Health

New research suggests that psychedelic drugs may work by strengthening specific brain connections linked to memory and cognition. Scientists found that under psychedelic exposure, neurons in the claustrum—a region dense with psychedelic-sensitive receptors—intensified their communication with the anterior cingulate cortex, a region involved in mood and psychiatric disorders.

Featured Neuroscience Psychology

·November 11, 2023·2 min read

Unraveling Psychedelics’ Potential in Mental Health

Research delves into the potential of psychedelics like psilocybin for treating psychiatric disorders. Studies show varying effects of psilocybin on fear learning in rats and mice, dependent on sex and dosage, and its potential to alleviate nicotine withdrawal in mice.

Featured Neuroscience Psychology

·April 25, 2023·3 min read

Enlightening Study Explores the Neurobiology of Psychedelics

Researchers studied the brain activity of healthy participants under the influence of nitrous oxide, comparing it to data from studies with ketamine and LSD to see whether the neurobiology of the psychedelic experience was similar. They found that the patterns of activity associated with the different substances overlapped, indicating common underlying biology, which could inform future research on the therapeutic use of psychedelics.

Featured Neuroscience Pain Psychology

·July 25, 2021·4 min read

The Future of Psychedelic Science

From treating depression and other mental health disorders, to helping relieve chronic pain, researchers discuss the advantages and implications of psychedelic treatments.

Featured Neurology Neuroscience Pain Psychology

·October 2, 2025·6 min read

Psilocybin Rewire Brain Circuits Tied to Pain and Mood

New research shows that psilocybin, the active compound in psychedelic mushrooms, can reduce both chronic pain and pain-related depression by modulating brain circuits rather than acting at the site of injury. In mouse studies, a single dose provided pain relief and mood benefits lasting nearly two weeks by targeting the anterior cingulate cortex.