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prozac

This image shows the serotonin pathway in the brain.

Featured Open Neuroscience Articles Psychology

·December 9, 2013·4 min read

A Personal Antidepressant for Every Genome

Researchers discover a gene which may reveal how well a person is likely to respond to SSRI antidepressants.

Illustration of the brain with amygdala highlighted.

Featured Neurology Psychology

·September 1, 2015·5 min read

Blocking Memory Pathway Could Prevent PTSD

A new study reports that serotonin promotes the consolidation of traumatic memories following stress events. Additionally, SSRI medications which are commonly prescribed for PTSD may make the condition worse by enhancing the effects of serotonin.

This shows a person with pills in their hand

Featured Neurology Neuroscience Open Neuroscience Articles Psychology

·June 25, 2019·4 min read

Common antidepressants interact with opioid med to lessen pain relief

SSRI antidepressants, such as Prozac and Paxil, interact with opioid medications to make them less effective at providing relief from chronic pain. Tramadol relies on activation of the CYP2D6 enzyme to control pain, but SSRIs inhibit this enzyme. Researchers suggest prescribing different classes of antidepressants which do not suppress the enzyme may benefit those in need of opioid medications. Alternatively, non-opioid pain killers should be considered for those who can not switch from SSRIs.

Image shows an electroconvulsive therapy machine on display at Glenside Museum.

Featured Neuroscience Videos Psychology

·January 13, 2017·7 min read

Electroconvulsive Therapy: A History Of Controversy, But Also Of Help

A new paper looks at the controversial use of electroconvulsive therapy over the years to treat depression.

Featured Neuroscience Open Neuroscience Articles Psychology

·November 8, 2021·4 min read

Expectations and Dopamine Can Affect Outcome of SSRI Antidepressant Treatment

The placebo effect combined with dopamine levels can determine whether symptoms of depression and social anxiety will improve in patients prescribed SSRI antidepressants. Researchers found the positive effect of the medications was four times higher in patients with high expectations the treatment would work compared to those with lower expectations.

Featured Neuroscience Psychology

·July 10, 2019·2 min read

How a popular antidepressant drug could rewire the brain

Fluoxetine rearranges nerve fibers in the hippocampus of mice, a new study reports.

Featured Neuroscience Psychology

·November 15, 2022·11 min read

How Do SSRIs Like Prozac, Lexapro Really Work? Ask a Fruit Fly

Researchers shed light on how different SSRI antidepressants may work to help fight symptoms of depression in the brain.

Featured Neuroscience Psychology

·September 6, 2019·5 min read

How serotonin and a popular anti-depressant affect the gut’s microbiota

Serotonin and SSRIs like Prozac can have a major effect on gut bacteria. When exposed to serotonin, specific gut bacteria grew to higher levels. However, when exposed to SSRIs, the bacterium grew to much lower levels in mouse models.