Study reveals a signaling pathway that controls the formation of synapses between pyramidal neurons and inhibitory neurons expressing the parvalbumin protein.
ISRIB, a synthetic molecule capable of boosting protein synthesis, restored memory function in mouse models of Alzheimer's disease and restored protein synthesis in the hippocampus.
A new Neuron study reports blocking the action of the mTORC1 protein causes mice to stop problem drinking behaviors. The findings could help develop new treatments for addictive behaviors in people.
Brain dysfunction noted in schizophrenia patients may be a result of impaired expression of a protein complex associated with protein synthesis, researchers report.
According to a new study, the brain blocks the ability for creating new memories shortly after waking in order to prevent the disruption of the stabilization of memory consolidation that occurs during sleep.
A new study identifies a sub region of the brain that works to form a particular kind of memory: fear-associated with a specific environmental cue or “contextual fear memory."
Researchers have devised a new way to map the transcriptome. In the process, they have revealed important variations in protein synthesis. The approach could have implications for furthering understanding of neurodegenerative diseases.
Two new studies are helping to enhance how schizophrenia affects the workings of the brain and opens new approaches for future treatment options.
Researchers have identified how neural stem cells remain relatively free of age related damage.