Optimized Sensors to Study Memory and Learning
A new biosensor can help visualize two proteins critical for synaptic plasticity, a new study reports.... Read More...
PKA
Researchers Identify Dopamine Signaling Pathway that Controls Cocaine Reward in Mice
A new study reports cocaine increases dopamine levels in the striatum, activating a previously unknown pathway.... Read More...
Strengthening Brain Connections
Researchers have identified a mechanism which allows the brain to strengthen links between neurons.... Read More...
Does Genetic Research Offer Hope for Autism Cure?
A new study suggests how researchers may combine different genetic approaches in search for a cure for autism.... Read More...
A Single Genetic Mutation May Cause Autism
A new study is the first to show how a single mutation disables a molecular switch in one of the more than 1000 autism genes and causes the disorder.... Read More...
Brain Enzyme is Double Whammy for Alzheimer’s Disease
Researchers discover that an enzyme known for generating toxic brain plaques in Alzheimer's disease also causes additional memory and cognitive deficits via a separate mechanism. They found that BACE1 disrupts the cell's production of other molecules required for PKA function. By that mechanism, BACE1 inactivates PKA and therefore inhibits memory formation in mice, even in the absence of neurotoxic β-amyloid.... Read More...