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Picower Institute for Learning and Memory

·May 22, 2023·5 min read

Cytoelectric Coupling: Electrical Fields Fine-Tune Brain Functioning

Scientists present a hypothesis dubbed "Cytoelectric Coupling" suggesting electrical fields within the brain can manipulate neuronal sub-cellular components, optimizing network stability and efficiency. They propose these fields allow neurons to tune the information processing network down to the molecular level.

This shows the outline of a woman's head and brain

Featured Neuroscience

·April 11, 2022·8 min read

A Single Memory Is Stored Across Many Connected Brain Regions

Brain mapping study reveals memory engrams are widely distributed throughout the brain, including among regions not previously realized.

This shows synapses and neurons imaged with the new method

Featured Neuroscience

·January 13, 2022·6 min read

Next-Generation Tissue Expansion Method Improves Neural Imaging

Researchers have developed a new method that vastly improves the imaging of the structures of neural connections using standard confocal microscopes.

This shows a brain and a lightening bolt

Featured Neurology Neuroscience

·May 16, 2022·5 min read

Circuit Model May Explain How Deep Brain Stimulation Treats Parkinson’s Disease Symptoms

A new computer model shows the beneficial effects of deep brain stimulation arise from how it interrupts the cycle promoting runway beta in a circuit loop between the subthalamic nucleus and striatum.

Featured Genetics Neurology Neuroscience

·January 4, 2021·3 min read

Scientists Seek Insight Into Parkinson’s, Addiction by Tracking Gene Expression in the Brain

New studies are set to explore how gene expression alters the brain's response to drug abuse, and to screen for genes that could help brain cells withstand Parkinson's disease.

Featured Neuroscience

·April 6, 2023·5 min read

Studying Consciousness Without Affecting It

Researchers found a way to assess consciousness without external stimulation, using a little-used approach where volunteers squeeze a force sensor with their hand when they breathe in and release it when they breathe out, resulting in more precise and sensitive measurements that may help improve treatment for insomnia and coma reversal.

Featured Neuroscience

·March 10, 2023·5 min read

Astrocyte Cells Critical for Learning Skilled Movements

Study reveals two specific ways in which astrocytes directly impact motor learning.

Featured Genetics Neurology

·July 22, 2020·6 min read

Neural Vulnerability in Huntington’s Disease Tied to Release of Mitochondrial RNA

In both human cell and mouse models of Huntington's disease, RNA from mitochondria was misplaced within spiny projection neurons. The stray RNAs, which looked different to cells than RNA derived from the cell nucleus, trigger an immune reaction that can lead to striatal cell type vulnerability.

This shows glutamate docking to the cell membrane

Featured Neuroscience Open Neuroscience Articles

·November 29, 2021·6 min read

Study Reveals a Protein’s Key Contribution to Heterogeneity of Neurons

Just one protein situated on the synapse can profoundly alter how some neurons communicate and implement plasticity.

Featured Neuroscience Open Neuroscience Articles

·September 6, 2022·6 min read

How the Brain Focuses on What’s in Mind

Rhythmic bursts of activity in the prefrontal cortex reduce variability as an animal focuses on a task.

Featured Neuroscience

·November 2, 2020·5 min read

Specific Brain Region and Circuits Controlling Attention Identified

Study identifies a key role locus coeruleus neurons play in attentional control.

Featured Neuroscience Visual Neuroscience

·June 9, 2021·6 min read

As Novel Sights Become Familiar, Different Brain Rhythms and Neurons Take Over

As novel visual patterns become familiar, stark changes occur in the visual cortex. Gamma rhythms give way to low-wave beta waves, and the neural activity switches from PV neurons in favor of inhibitory SOM neurons.

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Picower Institute for Learning and Memory

Cytoelectric Coupling: Electrical Fields Fine-Tune Brain Functioning

A Single Memory Is Stored Across Many Connected Brain Regions

Next-Generation Tissue Expansion Method Improves Neural Imaging

Circuit Model May Explain How Deep Brain Stimulation Treats Parkinson’s Disease Symptoms

Scientists Seek Insight Into Parkinson’s, Addiction by Tracking Gene Expression in the Brain

Studying Consciousness Without Affecting It

Astrocyte Cells Critical for Learning Skilled Movements

Neural Vulnerability in Huntington’s Disease Tied to Release of Mitochondrial RNA

Study Reveals a Protein’s Key Contribution to Heterogeneity of Neurons

How the Brain Focuses on What’s in Mind

Specific Brain Region and Circuits Controlling Attention Identified

As Novel Sights Become Familiar, Different Brain Rhythms and Neurons Take Over

Meditation Diminishes Bias Toward Negative Information

AI Can Predict Preterm Birth at 31 Weeks of Gestation

Middle Age Sexual Satisfaction: A Potential Early Sign of Cognitive Decline

Sleep Apnea’s Deep Impact on Gene Activity

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