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          Picower Institute for Learning and Memory

          This shows an organoid
          FeaturedGeneticsNeuroscienceOpen Neuroscience Articles
          ·December 8, 2020·6 min read

          ‘SCOUT’ Helps Researchers Find, Quantify Significant Differences Among Organoids

          SCOUT is a newly developed pipeline for clearing, labeling, 3D imaging, and analyzing cerebral organoids.
          Read More
          This shows synapses and neurons imaged with the new method
          FeaturedNeuroscience
          ·January 13, 2022·6 min read

          Next-Generation Tissue Expansion Method Improves Neural Imaging

          Researchers have developed a new method that vastly improves the imaging of the structures of neural connections using standard confocal microscopes.
          Read More
          This shows a graph from the study
          FeaturedNeuroscience
          ·September 11, 2020·5 min read

          As Information Flows Through Brain’s Heirarchy, Higher Regions Use Higher Frequency Waves

          Study provides new insight into how brain waves control the flow of information through the cortex.
          Read More
          This shows neurons
          FeaturedNeuroscienceOpen Neuroscience Articles
          ·July 23, 2022·8 min read

          How Neurons Build and Maintain Their Capacity to Communicate

          Researchers reveal how neurons set up and sustain the vital infrastructure that allows for seamless neurotransmission.
          Read More
          This shows interneurons in the visual cortex
          FeaturedNeuroscienceVisual Neuroscience
          ·September 8, 2021·7 min read

          Behind the Scenes, Brain Circuit Ensures Vision Remains Reliable

          While some types of excitatory neurons respond to images and represent them in the visual cortex, the activity of two types of inhibitory interneurons combine in a circuit to reinforce visual stability and reliability.
          Read More
          This shows a mouse brain slice
          FeaturedNeurologyNeuroscience
          ·April 19, 2023·6 min read

          Neurons Vulnerable to Alzheimer’s Identified

          Researchers identified a subset of neurons in the mammillary body of the hypothalamus which are susceptible to hyperactivity and neurodegeneration. This damage often leads to memory impairment associated with Alzheimer's disease. Treating these neurons with a drug currently used in the treatment of epilepsy reverses memory impairments caused by this hyperactivity and neurodegeneration.
          Read More
          This shows the outline of a head
          FeaturedNeuroscience
          ·April 27, 2022·6 min read

          Anesthetic Drastically Diverts the Travels of Brain Waves

          New findings reveal how anesthesia-induced unconsciousness differs from normal sleep in relation to delta wave activity in the brain.
          Read More
          This shows a brain
          FeaturedNeuroscience
          ·November 24, 2020·7 min read

          Brain Waves Guide Us in Spotlighting Surprises

          A dynamic interplay of different brainwave frequencies, not dedicated networks, governs how the brain acts to a novel surprise and downplays predictable stimuli.
          Read More
          This shows a woman under anesthesia.
          FeaturedNeuroscience
          ·November 8, 2023·7 min read

          How Anesthesia Blocks Consciousness

          A new study reveals insights into how general anesthesia affects consciousness and sensory perception. Using animal models, researchers found that while propofol anesthesia allows sensory information to reach the brain, it disrupts the spread of signals across the cortex.
          Read More
          This shows a mouse brain and what looks like computer chips
          FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles
          ·February 23, 2021·6 min read

          Basic Cell Health Systems Wear Down in Huntington’s Disease

          Huntington's disease may progress to advanced stages as a result of degradation of the cells' health maintenance system than due to the increased disease pathology itself.
          Read More
          This shows a brain and a lightening bolt
          FeaturedNeurologyNeuroscience
          ·May 16, 2022·5 min read

          Circuit Model May Explain How Deep Brain Stimulation Treats Parkinson’s Disease Symptoms

          A new computer model shows the beneficial effects of deep brain stimulation arise from how it interrupts the cycle promoting runway beta in a circuit loop between the subthalamic nucleus and striatum.
          Read More
          This shows a mouse in a maze.
          FeaturedNeuroscience
          ·September 15, 2023·8 min read

          Mice in Maze Shed New Light on Rodent Learning and Cognition

          Researchers have delved deeper into mouse behavior, challenging previous assumptions about their cognitive strategies in reward-based learning tasks. While humans efficiently adopt the "win-stay, lose-shift" approach in "reversal learning" activities, mice were observed to blend this with an exploratory strategy.
          Read More
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          This shows wasabi powder.

          Wasabi Compound Enhances Memory

          This shows a young pregnant woman.

          Genes Associated with Earlier and Higher Reproduction Linked to Accelerated Aging

          This shows a woman in a wheelchair.

          Novel Multiple Sclerosis Treatment Shows Promise

          This shows a brain.

          Brain’s Response to Crucial Language Hub Removal: New Insights

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