Picower Institute for Learning and Memory

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Picower Institute for Learning and Memory

·July 22, 2020·6 min read

Neural Vulnerability in Huntington’s Disease Tied to Release of Mitochondrial RNA

In both human cell and mouse models of Huntington's disease, RNA from mitochondria was misplaced within spiny projection neurons. The stray RNAs, which looked different to cells than RNA derived from the cell nucleus, trigger an immune reaction that can lead to striatal cell type vulnerability.

Featured Neuroscience

·September 11, 2020·5 min read

As Information Flows Through Brain’s Heirarchy, Higher Regions Use Higher Frequency Waves

Study provides new insight into how brain waves control the flow of information through the cortex.

Featured Neuroscience

·September 17, 2020·6 min read

Live Imaging Method Brings Structural Information to Mapping of Brain Function

Structural and functional coupling in visual areas of the mouse brain can be detected at sub-cellular resolution in vitro.

Featured Genetics Neurology Open Neuroscience Articles

·October 6, 2020·6 min read

Alzheimer’s Risk Gene Disrupts Endocytosis, but Another Disease-Linked Gene Could Help

The Alzheimer's risk gene ApoE4 hampers the process of endocytosis in astrocytes.

Featured Neuroscience

·November 2, 2020·5 min read

Specific Brain Region and Circuits Controlling Attention Identified

Study identifies a key role locus coeruleus neurons play in attentional control.

Featured Neuroscience

·November 24, 2020·7 min read

Brain Waves Guide Us in Spotlighting Surprises

A dynamic interplay of different brainwave frequencies, not dedicated networks, governs how the brain acts to a novel surprise and downplays predictable stimuli.

Featured Neuroscience Open Neuroscience Articles

·November 30, 2020·7 min read

Cortex Over Reflex: Study Traces Circuits Where Executive Control Overcomes Instinct

Anterior cingulate cortex neurons project connections to the superior colliculus. The superior colliculus carries out reflexive movements. The study finds the purpose of the ACC neurons connections to the SC is to over-rider the SC when executive control is essential.

Featured Genetics Neuroscience Open Neuroscience Articles

·December 8, 2020·6 min read

‘SCOUT’ Helps Researchers Find, Quantify Significant Differences Among Organoids

SCOUT is a newly developed pipeline for clearing, labeling, 3D imaging, and analyzing cerebral organoids.

Featured Genetics Neurology Neuroscience

·January 4, 2021·3 min read

Scientists Seek Insight Into Parkinson’s, Addiction by Tracking Gene Expression in the Brain

New studies are set to explore how gene expression alters the brain's response to drug abuse, and to screen for genes that could help brain cells withstand Parkinson's disease.

This shows how the memory switches in the brain

Featured Neuroscience Visual Neuroscience

·February 8, 2021·7 min read

As You Look Around, Mental Images Bounce Between Right and Left Brain

In visual working memory, the brain immediately transfers the memory of object shifts by re-encoding the memory among neurons in the opposite brain hemisphere.

This shows a mouse brain and what looks like computer chips

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·February 23, 2021·6 min read

Basic Cell Health Systems Wear Down in Huntington’s Disease

Huntington's disease may progress to advanced stages as a result of degradation of the cells' health maintenance system than due to the increased disease pathology itself.

Featured Neurology Neuroscience Open Neuroscience Articles

·April 27, 2021·5 min read

Anesthesia Doesn’t Simply Turn Off the Brain, It Changes Its Rhythms

Propofol, the commonly used anesthetic, alters and controls the dynamics of the brain's rhythms. The findings can help doctors better monitor patients under anesthesia with the aid of EEG.

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