In both human cell and mouse models of Huntington's disease, RNA from mitochondria was misplaced within spiny projection neurons. The stray RNAs, which looked different to cells than RNA derived from the cell nucleus, trigger an immune reaction that can lead to striatal cell type vulnerability.
Study provides new insight into how brain waves control the flow of information through the cortex.
Structural and functional coupling in visual areas of the mouse brain can be detected at sub-cellular resolution in vitro.
Study identifies a key role locus coeruleus neurons play in attentional control.
Anterior cingulate cortex neurons project connections to the superior colliculus. The superior colliculus carries out reflexive movements. The study finds the purpose of the ACC neurons connections to the SC is to over-rider the SC when executive control is essential.
New studies are set to explore how gene expression alters the brain's response to drug abuse, and to screen for genes that could help brain cells withstand Parkinson's disease.
In visual working memory, the brain immediately transfers the memory of object shifts by re-encoding the memory among neurons in the opposite brain hemisphere.
Huntington's disease may progress to advanced stages as a result of degradation of the cells' health maintenance system than due to the increased disease pathology itself.
Propofol, the commonly used anesthetic, alters and controls the dynamics of the brain's rhythms. The findings can help doctors better monitor patients under anesthesia with the aid of EEG.