Researchers report a 37 percent increase in speech or language disorders in the offspring of mothers who used SSRI antidepressants while pregnant.
A new study reports an antidepressant temporarily inhibits the blood-brain barrier, allowing drugs to enter the brain. The findings could have implications for treating neurological diseases from ALS to epilepsy.
Interferon-a2b an antiviral treatment shows promise in helping to speed up the recovery of patients with severe COVID-19 infections. IFN-a2b improves viral clearance and decreases the levels of inflammatory markers in coronavirus patients.
Study reveals statins are associated with a reduced risk of Alzheimer's disease, but the reduction of risk varied by race, ethnicity and statin type.
A new study backs previous findings, reporting a reduced risk of ASD in the offspring of mothers who used folic acid and multivitamins both prior to and during pregnancy.
Anakinra, a clinically approved anti-inflammatory used to treat rheumatoid arthritis, improves respiratory function in patients with severe COVID-19 infection.
UCSD has launched a Phase III clinical trial to assess whether tocilizumab (Actemra), a drug commonly prescribed for rheumatoid arthritis and other inflammatory disorders, has therapeutic value for those at risk of developing severe COVID-19 infection. The drug is a monoclonal antibody-based therapy that blocks receptors for interleukin-6, a cytokine that triggers inflammation as an early immune response to coronavirus. Blocking IL-6 could prevent the risk of the COVID-19 associated cytokine storm many with severe infection experience.
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A new deep learning algorithm helped researchers identify a powerful new antibiotic compound that kills many of the world's most problematic, disease-causing bacterias, including those which have so far been resistant to common antibiotics.
A new clinical trial is underway to test ibudilast, an asthma drug approved in Japan, for the treatment of severe COVID-19. Ibudilast is a MIF inhibitor. MIF is a gene that regulates immune response and is a driver of inflammation which results in the cytokine storm associated with coronavirus.
Research provides the first evidence that mechanisms regulated by the Runx1 gene control the balance between the surveillant versus activated microglia states.
Researchers discover a slightly increased risk of children developing autism if the mother had a fever during the second trimester of pregnancy. However, researchers found no cases of ASD in children of mothers who took ibuprofen to help manage the fever, a new study reports.
Felodipine, a common hypertension medication, induces autophagy and clears aggregate-prone proteins associated with neurodegenerative diseases. The study reveals the drug clears mutant alpha-synuclein in the brains of mice at plasma concentrations to those seen in humans taking the medication. Felodipine appears to have some neuroprotective properties in mouse models of neurodegenerative diseases.