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perineuronal nets

Featured Neurology Neuroscience Open Neuroscience Articles

·September 7, 2020·8 min read

The Brain Can Induce Diabetes Remission in Rodents, but How?

Researchers demonstrate how a single injection of fibroblast growth factor 1 (FGF1) can restore blood sugar levels to normal for extended periods in rodent models of type 2 diabetes. Studies show how FGF1 affects specific neurons and perineuronal nets to help restore blood sugar levels to normal, thus sending diabetes into remission.

Featured Neuroscience

·February 20, 2019·4 min read

Potential Link Between Vitamin D Deficiency and Loss of Brain Plasticity

Researchers report vitamin D levels affect perineuronal nets in the hippocampus. The study found vitamin D deficiency resulted in a significant decline in memory and learning in mouse models.

Featured Neuroscience

·July 27, 2020·3 min read

Changes in Brain Cartilage May Explain Why Sleep Helps You Learn

Altering the structure of perineuronal nets could be a mechanism that underlies sleep-induced memory changes.

Featured Neuroscience Open Neuroscience Articles

·July 22, 2021·5 min read

Age-Related Memory Loss Reversed In Mice

Reconstituting the amount of chondroitin 6-sulphate to perineuronal nets completely restored memory and brain plasticity in aging mice to a similar level as seen in younger animals, a new study reports. The findings could lead to new therapies to restore age-related memory loss in older humans.

Featured Psychology

·June 23, 2017·5 min read

How Hearing a Warning Sound Turns Into Fearing It Over Time: Mouse Study

Researchers identify a new mechanism that contributes to learning an association between a warning noise and a fearful event.

Brain Cancer Featured Neurology Neuroscience Open Neuroscience Articles

·November 9, 2018·5 min read

Researchers Solve Century Old Neuroscience Mystery

Researchers have solves a longstanding mystery relating to perineuronal nets, giving rise to potential new treatments for epilepsy. The study reports the nets modulate electrical impulses in the brain and seizures can occur if perineuronal networks are dissolved.

Featured Neuroscience

·June 5, 2019·3 min read

Bad diets making for bad memories

Perineuronal nets (PNNs) and the neurons they enmesh can be damaged by poor diets. Excessive consumption of foods high in saturated fats and refined sugars cause inflammation and oxidative stress, resulting in cognitive decline and poor memory.