A new study reveals pericyte degeneration may influence the development of Alzheimer's disease.
Capillary constriction caused by amyloid beta restricts cerebral blood flow in mouse models of Alzheimer's disease. Inhibiting the capillary constriction may potentially reduce some of the neurodegenerative features of Alzheimer's.
Pericytes could provide novel targets for the treatment and diagnosis of Alzheimer's disease, a new study reports.
Researchers use two-photon imaging and optogenetics to isolate and study brain capillaries in animal models.
Vascular cell loss results in neuron loss, researchers report. However, pericytes secrete a substance that helps protect neurons, even when vascular cell degeneration begins to occur.
Damaged capillaries in the brain may set the stage for the development of Alzheimer's disease, years before symptoms appear.
A newly created stem cell model demonstrates a potential route of entry of the COVID-19 virus, SARS_CoV_2, into the human brain.
Researchers improve the recovery of function in mice following spinal cord injury.