Parkinson’s disease

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Parkinson’s disease

Featured Genetics Neurology Neuroscience

·May 11, 2022·7 min read

Designer Neurons Offer New Hope for Treatment of Parkinson’s Disease

Researchers have designed a new method of converting non-neural cells into functioning neurons that are able to form synapses, dispense dopamine, and restore the function of neurons undermined by Parkinson's associated destruction of dopaminergic cells.

Featured Genetics Neurology Neuroscience

·May 15, 2022·3 min read

A Study Reveals One of the Reasons Why Neurons Die in Parkinson’s Patients

Study implicates the gene DJ1 in neuronal death associated with Parkinson's disease.

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Featured Neurology Neuroscience

·May 16, 2022·5 min read

Circuit Model May Explain How Deep Brain Stimulation Treats Parkinson’s Disease Symptoms

A new computer model shows the beneficial effects of deep brain stimulation arise from how it interrupts the cycle promoting runway beta in a circuit loop between the subthalamic nucleus and striatum.

Featured Neurology Neuroscience

·May 19, 2022·4 min read

How the Volumes of Brain Regions Change in Parkinson’s Disease

Volume decreases in cortical areas, the amygdala, and basal forebrain in Parkinson's patients correlated with worsening symptoms of the disease.

Featured Neurology Neuroscience Open Neuroscience Articles

·May 26, 2022·5 min read

A Biomarker That Can Diagnose Parkinson’s Disease

Researchers have developed a new biomarker that will enable a rapid and inexpensive test for Parkinson's disease.

Featured Neurology Neuroscience

·May 27, 2022·4 min read

On Your Back, Side, or Face-Down? How We Sleep May Trigger or Protect Our Brain From Diseases Like ALS

A new mouse study reveals our sleep position may influence the glymphatic system and could increase the risk of developing ALS or other neurodegenerative diseases.

Featured Neuroscience

·June 1, 2022·6 min read

Stretchable Probe Measures Brain Chemicals Central to Parkinson’s, Depression, and Gut Disease

A newly invented soft, implantable probe can interface between gut and brain tissue, measuring both dopamine and serotonin levels. The device has applications for depression, Parkinson's disease, and intestinal disorders.

Featured Neurology Neuroscience

·June 8, 2022·6 min read

Three Distinct Brain Circuits in the Thalamus Contribute to Parkinson’s Symptoms

Neurons in the parafascicular thalamus project to three different parts of the basal ganglia. Targeting these circuits could be a new target for treating motor dysfunction and depression associated with Parkinson's disease.

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Featured Neurology Neuroscience

·June 8, 2022·4 min read

Bad Dreams Could Be Early Warning of Parkinson’s Disease

Older adults who frequently experience bad dreams or nightmares are twice as likely to be diagnosed with Parkinson's disease, a new study reports.

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Featured Genetics Neurology Neuroscience

·June 9, 2022·5 min read

A ‘Double Life’ for a Key Parkinson’s Disease Protein

The Parkinson's-associated protein alpha-synuclein appears to act as a "toggle switch" that helps control vesicle transportation and gene expression. In a diseased state, this delicate balance is broken. The findings have implications for the development of new treatments for Parkinson's disease.

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Featured Neuroscience

·June 11, 2022·5 min read

Learning and Remembering Movement

Focusing on the largest pyramidal neurons in the motor cortex, researchers found dendritic branches do not simply pass movement information forward. Each sub-branch calculates the information and passes it to larger sub-branches, which in turn, perform the same operation. Multiple dendritic branchlets can interact with each other to amplify their combined computational product.

Featured Neurology Neuroscience Open Neuroscience Articles

·June 12, 2022·2 min read

A New Candidate Therapeutic Target for Parkinson’s Disease Identified

Researchers identified LIPE, a lipase that degrades triglycerides to produce fatty acids, as a potential new target for the development of treatments for Parkinson's disease.

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