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Parkinson’s disease

·October 8, 2024·4 min read

Immune Response Linked to Lewy Body Formation

New research reveals that immune responses play a crucial role in the formation of Lewy bodies, protein aggregates that mark Parkinson's disease and other neurological conditions. Using human stem cells, scientists recreated Lewy bodies in dopaminergic neurons by combining alpha-synuclein protein buildup with immune stimulation.

Featured Neurology Neuroscience

·October 5, 2024·5 min read

New Molecule Offers Hope for Parkinson’s by Outperforming L-Dopa

A new study has discovered that ophthalmic acid, a molecule in the brain, acts like a neurotransmitter to regulate motor function, similar to dopamine. In Parkinson’s mouse models, this molecule improved movement for over 20 hours—far longer than the effects of the current treatment, L-dopa.

Featured Neuroscience Psychology Visual Neuroscience

·October 1, 2024·5 min read

Reduced Brain Response to Visual Cues Linked to Psychosis in Parkinson’s

People with Parkinson's disease (PD) who experience visual hallucinations have reduced brain responses to unexpected visual changes, a marker known as visual mismatch negativity (vMMN). Using EEG, researchers compared brain activity in PD patients with and without hallucinations and discovered that those with hallucinations showed weaker vMMN signals.

Featured Neurology Neuroscience

·September 30, 2024·5 min read

Right-Sided DBS: Effective Parkinson’s Treatment Without Speech Loss

A new study has shown that unilateral deep brain stimulation (DBS) on the right side of the brain improves motor symptoms in Parkinson's patients without causing significant declines in verbal fluency. Researchers found that DBS on the left hemisphere led to more noticeable declines in word retrieval and generation.

Featured Neurology Neuroscience

·September 27, 2024·8 min read

Improving Voice Recognition for People with Speech Disabilities

A new study shows that automatic speech recognition (ASR) systems trained on speech from people with Parkinson’s disease are 30% more accurate in transcribing similar speech patterns. Researchers collected over 151 hours of recordings from participants with varying degrees of dysarthria, a speech disorder common in Parkinson’s patients, and used the data to train ASR systems.

Featured Neurology Neuroscience

·September 27, 2024·5 min read

Metabolic Disruptions in Parkinson’s Uncover New Treatment Potential

A new study has revealed critical metabolic impairments in Parkinson’s disease (PD), focusing on purine metabolism and ATP recycling. Researchers found that patients with PD have significantly lower levels of uric acid and other purine metabolites in their blood and cerebrospinal fluid, affecting energy production in the brain.

Featured Genetics Neurology Neuroscience

·September 26, 2024·3 min read

Newly Found Genetic Mutation Linked to Early-Onset Parkinson’s

A new study led by scientists has uncovered a mutation in the SGIP1 gene that may cause early-onset Parkinson's. The discovery, based on a family with a history of the disease, sheds light on how this mutation disrupts brain cell communication.

Featured Neurology Neuroscience

·September 24, 2024·5 min read

Parkinson’s Drug Linked to Impaired Decision-Making

Pramipexole, a Parkinson’s disease (PD) drug, impairs decision-making by hyperactivating the brain’s external globus pallidus (GPe) region. This research uncovers how the medication, while effective for PD symptoms, can lead to risky behaviors like gambling.

Featured Neurology Neuroscience

·September 8, 2024·4 min read

Are Smokers Really Less Likely to Develop Parkinson’s?

Low doses of carbon monoxide, similar to levels experienced by smokers, can protect against neurodegeneration in Parkinson’s disease models. Researchers discovered that carbon monoxide reduced the accumulation of the Parkinson’s-associated protein alpha-synuclein and activated pathways that limit oxidative stress.

Featured Neurology Neuroscience

·September 7, 2024·5 min read

Upper GI Damage Linked to 76% Higher Parkinson’s Disease Risk

People with a history of upper gastrointestinal (GI) damage have a 76% higher risk of developing Parkinson’s disease. The research highlights how conditions like GERD, peptic ulcers, and NSAID use may increase the risk of this neurodegenerative disorder.

Featured Neurology Neuroscience

·August 8, 2024·3 min read

Lower Dementia Risk Than Previously Thought in Parkinson’s

A new study suggests that the risk of developing dementia in Parkinson’s disease patients may be lower or occur later than previously reported. Researchers analyzed data from two large studies, finding a 9% risk of dementia within 10 years for newly diagnosed patients and a 27% risk for those diagnosed for an average of six years. Factors increasing dementia risk included older age at diagnosis, being male, and lower education levels.

This shows a brain surrounded by seaweed.

Featured Neurology Neuroscience

·August 5, 2024·3 min read

Seaweed Antioxidants Show Promise in Preventing Parkinson’s

Researchers have found that antioxidants from Ecklonia cava, a type of seaweed, may help prevent Parkinson's disease by protecting dopamine-producing neurons. In mouse models, these antioxidants restored motor function and improved gut health after exposure to toxins. Cellular studies revealed that these compounds activate the AMPK enzyme and reduce harmful reactive oxygen species, potentially offering a new approach to combat neurodegeneration. This discovery highlights the potential of Ecklonia cava as a preventive ingredient against Parkinson's disease.

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Parkinson’s disease

Immune Response Linked to Lewy Body Formation

New Molecule Offers Hope for Parkinson’s by Outperforming L-Dopa

Reduced Brain Response to Visual Cues Linked to Psychosis in Parkinson’s

Right-Sided DBS: Effective Parkinson’s Treatment Without Speech Loss

Improving Voice Recognition for People with Speech Disabilities

Metabolic Disruptions in Parkinson’s Uncover New Treatment Potential

Newly Found Genetic Mutation Linked to Early-Onset Parkinson’s

Parkinson’s Drug Linked to Impaired Decision-Making

Are Smokers Really Less Likely to Develop Parkinson’s?

Upper GI Damage Linked to 76% Higher Parkinson’s Disease Risk

Lower Dementia Risk Than Previously Thought in Parkinson’s

Seaweed Antioxidants Show Promise in Preventing Parkinson’s

New Study Uncovers the Structural Key to How Cells Ship Cargo

Meditation Retreat Sparks Rapid Brain & Immune System Changes

AI-Driven Brain Implant Brings “Two-Way” Artificial Vision Closer to Reality

Oxidative Stress May Drive Repetitive Behaviors Linked to Autism, OCD

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