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          Parkinson’s disease

          This shows neurons.
          FeaturedNeurologyNeuroscience
          ·September 27, 2024·5 min read

          Metabolic Disruptions in Parkinson’s Uncover New Treatment Potential

          A new study has revealed critical metabolic impairments in Parkinson’s disease (PD), focusing on purine metabolism and ATP recycling. Researchers found that patients with PD have significantly lower levels of uric acid and other purine metabolites in their blood and cerebrospinal fluid, affecting energy production in the brain.
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          This shows neurons.
          FeaturedGeneticsNeurologyNeuroscience
          ·September 26, 2024·3 min read

          Newly Found Genetic Mutation Linked to Early-Onset Parkinson’s

          A new study led by scientists has uncovered a mutation in the SGIP1 gene that may cause early-onset Parkinson's. The discovery, based on a family with a history of the disease, sheds light on how this mutation disrupts brain cell communication.
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          This shows neurons.
          FeaturedNeurologyNeuroscience
          ·September 24, 2024·5 min read

          Parkinson’s Drug Linked to Impaired Decision-Making

          Pramipexole, a Parkinson’s disease (PD) drug, impairs decision-making by hyperactivating the brain’s external globus pallidus (GPe) region. This research uncovers how the medication, while effective for PD symptoms, can lead to risky behaviors like gambling.
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          This shows a brain surrounded by smoke.
          FeaturedNeurologyNeuroscience
          ·September 8, 2024·4 min read

          Are Smokers Really Less Likely to Develop Parkinson’s?

          Low doses of carbon monoxide, similar to levels experienced by smokers, can protect against neurodegeneration in Parkinson’s disease models. Researchers discovered that carbon monoxide reduced the accumulation of the Parkinson’s-associated protein alpha-synuclein and activated pathways that limit oxidative stress.
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          This shows a neuron.
          FeaturedNeurologyNeuroscience
          ·September 7, 2024·5 min read

          Upper GI Damage Linked to 76% Higher Parkinson’s Disease Risk

          People with a history of upper gastrointestinal (GI) damage have a 76% higher risk of developing Parkinson’s disease. The research highlights how conditions like GERD, peptic ulcers, and NSAID use may increase the risk of this neurodegenerative disorder.
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          This shows an older man.
          FeaturedNeurologyNeuroscience
          ·August 8, 2024·3 min read

          Lower Dementia Risk Than Previously Thought in Parkinson’s

          A new study suggests that the risk of developing dementia in Parkinson’s disease patients may be lower or occur later than previously reported. Researchers analyzed data from two large studies, finding a 9% risk of dementia within 10 years for newly diagnosed patients and a 27% risk for those diagnosed for an average of six years. Factors increasing dementia risk included older age at diagnosis, being male, and lower education levels.
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          This shows a brain surrounded by seaweed.
          FeaturedNeurologyNeuroscience
          ·August 5, 2024·3 min read

          Seaweed Antioxidants Show Promise in Preventing Parkinson’s

          Researchers have found that antioxidants from Ecklonia cava, a type of seaweed, may help prevent Parkinson's disease by protecting dopamine-producing neurons. In mouse models, these antioxidants restored motor function and improved gut health after exposure to toxins. Cellular studies revealed that these compounds activate the AMPK enzyme and reduce harmful reactive oxygen species, potentially offering a new approach to combat neurodegeneration. This discovery highlights the potential of Ecklonia cava as a preventive ingredient against Parkinson's disease.
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          This shows stem cells.
          FeaturedGeneticsNeurologyNeuroscience
          ·July 29, 2024·5 min read

          Rapid Stem Cell Model Advances Parkinson’s Research

          Researchers have developed a model that quickly converts stem cells to brain cells with Parkinson’s disease (PD) protein structures, allowing for personalized study and treatment. This new approach can transform stem cells into brain cells within weeks, facilitating high-throughput genetic and drug screening. By mimicking diverse protein misfolding seen in PD patients, the model offers a practical tool for diagnostics and drug discovery. This advancement could lead to personalized therapies for Parkinson's and related neurodegenerative diseases.
          Read More
          This shows a neuron.
          FeaturedNeurologyNeuroscience
          ·July 16, 2024·5 min read

          AI Identifies Three Parkinson’s Subtypes

          Researchers used machine learning to identify three subtypes of Parkinson’s disease based on progression speed. These subtypes, marked by distinct genetic drivers, could enhance diagnosis and treatment strategies.
          Read More
          This shows a person with clouds around their head.
          FeaturedNeurologyNeurosciencePsychology
          ·June 25, 2024·3 min read

          Anxiety Doubles Parkinson’s Risk

          Researchers found that people over 50 with anxiety have twice the risk of developing Parkinson’s disease. Using UK primary care data from 2008-2018, the study compared 109,435 patients with anxiety to 878,256 without. Results showed increased Parkinson’s risk and identified additional risk factors like depression and sleep problems. This research suggests early detection and treatment for Parkinson’s might be possible by monitoring anxiety and related symptoms.
          Read More
          This shows blood vials.
          FeaturedNeurologyNeuroscience
          ·June 18, 2024·6 min read

          Blood Test Predicts Parkinson’s Years Before Symptoms

          Researchers have developed an AI-powered blood test that can predict Parkinson's disease up to seven years before symptoms appear. The test analyzes eight blood biomarkers and has shown 100% accuracy in diagnosing the disease. This breakthrough offers the potential for early intervention and treatment before significant damage occurs in the brain.
          Read More
          This shows bacteria.
          FeaturedGeneticsNeurologyNeuroscience
          ·June 18, 2024·5 min read

          Vitamin B Deficiency in Gut Linked to Parkinson’s

          A new study reveals a link between gut bacteria and Parkinson's disease (PD). Researchers found a decrease in genes responsible for synthesizing essential B vitamins in PD patients, which may weaken the intestinal barrier and lead to inflammation in the brain. This finding suggests that B vitamin supplementation could be a potential therapeutic avenue for PD.
          Read More
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          AI Tool Flags Predatory Journals, Building a Firewall for Science

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          Genetics Reveal How Human Contact Shapes Language Evolution

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          Most Autistic Adults Over 40 Remain Undiagnosed

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          “Junk DNA” Plays Key Role in Brain Development and Disease

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