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Parkinson’s disease

Auditory Neuroscience Featured Neurology Neuroscience

·January 14, 2025·5 min read

Hearing Loss May Signal Increased Risk of Parkinson’s Disease

A new study has identified a potential link between hearing impairment and an increased risk of developing Parkinson’s disease. Researchers analyzed data from over 159,000 individuals, finding that every 10-decibel increase in hearing loss corresponded to a 57% higher risk of Parkinson’s.

Featured Neurology Neuroscience

·January 3, 2025·5 min read

Ketamine Offers Hope for Parkinson’s Treatment-Linked Dyskinesia

Researchers have uncovered a new understanding of levodopa-induced dyskinesia, a common side effect in Parkinson’s patients, revealing that the motor cortex disconnects rather than directly causing these movements.

Featured Neurology Neuroscience

·December 16, 2024·4 min read

Accurate Parkinson’s Detection via Emotional Brain Responses

A new study has achieved near-perfect accuracy in detecting Parkinson's disease by analyzing brain responses to emotional stimuli using EEG and AI. Researchers found that Parkinson's patients process emotions differently, struggling with recognizing fear, disgust, and surprise and focusing more on emotional intensity than valence.

This shows chemical imaging of the microbiome.

Featured Neurology Neuroscience

·November 21, 2024·5 min read

Parkinson’s Medication Alters Microbiome, Induces Iron Deficiency

The Parkinson's drug entacapone disrupts the gut microbiome by inducing iron deficiency, favoring the growth of potentially harmful bacteria like E. coli. Using advanced molecular techniques, researchers identified that entacapone interferes with iron availability, a critical resource for many gut microbes.

Featured Neurology Neuroscience

·November 18, 2024·7 min read

Parkinson’s Tremor Linked to Dopamine in Caudate Nucleus

Rest tremor in Parkinson’s disease is linked to dopamine activity in the caudate nucleus, challenging conventional beliefs about dopamine loss and motor symptoms. Surprisingly, patients with stronger tremor preserved more dopamine in the caudate, highlighting a complex relationship between tremor severity and neural circuits.

Featured Genetics Neurology Neuroscience

·November 13, 2024·6 min read

Parkinson’s Progression Linked to New Protein Pathway

Researchers have identified a protein, TMEM16F, that appears to aid the spread of Parkinson’s pathology in the brain. They found that a mutation in this protein promotes the secretion of a harmful form of α-synuclein, which moves through nerve cells, forming toxic Lewy bodies.

Featured Genetics Neurology Neuroscience

·November 3, 2024·3 min read

RNA Structures Linked to Parkinson’s Protein Aggregates

Researchers have identified unique RNA structures called G-quadruplexes (G4s) that promote harmful α-synuclein protein aggregation linked to neurodegenerative diseases like Parkinson’s. Elevated calcium levels trigger these G4s, acting as "scaffolds" for α-synuclein clumping. Administering 5-aminolevulinic acid (5-ALA) to model mice prevented aggregation and reduced motor symptoms. This breakthrough suggests that G4-targeted therapies could offer early intervention for neurodegenerative diseases.

Featured Neurology Neuroscience

·November 2, 2024·8 min read

New Blood Test Shows Promise for Early Parkinson’s Detection

Researchers have developed a method to analyze extracellular vesicles (EVs) in blood for early detection of Parkinson’s disease (PD). By isolating EVs and assessing their contents, the team identified a protein called phosphorylated α-synuclein that appears in elevated levels in PD patients.

Featured Neurology Neuroscience

·October 23, 2024·5 min read

Penicillin Use Linked to Lower Parkinson’s Risk

A new study found that people who took multiple courses of penicillin antibiotics had a 15% lower risk of developing Parkinson's disease. Researchers analyzed medical records of over 93,000 individuals and discovered a connection between gut health and the disease, suggesting that altering the gut microbiome may influence Parkinson’s risk.

Featured Genetics Neurology Neuroscience

·October 21, 2024·5 min read

Genetic Variants Linked to Brain Volume Shed Light on ADHD, Parkinson’s

A large-scale study identified 254 genetic variants that shape the volume of key brain regions responsible for memory, motor control, and behavior. Researchers analyzed DNA and brain scans from nearly 75,000 people, uncovering links between these variants and conditions like ADHD and Parkinson’s disease.

This shows a brain and a person sleeping.

Featured Neurology Neuroscience

·October 18, 2024·3 min read

REM Sleep-Inducing Neurons Identified

Researchers have discovered two neuron types in the brainstem that induce REM sleep, shedding light on the mechanisms behind this crucial sleep phase. These neurons form circuits that control brain activity, eye movement, and muscle tone loss during REM sleep.

Featured Neurology Neuroscience

·October 8, 2024·4 min read

Immune Response Linked to Lewy Body Formation

New research reveals that immune responses play a crucial role in the formation of Lewy bodies, protein aggregates that mark Parkinson's disease and other neurological conditions. Using human stem cells, scientists recreated Lewy bodies in dopaminergic neurons by combining alpha-synuclein protein buildup with immune stimulation.

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Parkinson’s disease

Hearing Loss May Signal Increased Risk of Parkinson’s Disease

Ketamine Offers Hope for Parkinson’s Treatment-Linked Dyskinesia

Accurate Parkinson’s Detection via Emotional Brain Responses

Parkinson’s Medication Alters Microbiome, Induces Iron Deficiency

Parkinson’s Tremor Linked to Dopamine in Caudate Nucleus

Parkinson’s Progression Linked to New Protein Pathway

RNA Structures Linked to Parkinson’s Protein Aggregates

New Blood Test Shows Promise for Early Parkinson’s Detection

Penicillin Use Linked to Lower Parkinson’s Risk

Genetic Variants Linked to Brain Volume Shed Light on ADHD, Parkinson’s

REM Sleep-Inducing Neurons Identified

Immune Response Linked to Lewy Body Formation

Oral Bacteria May Drive Multiple Sclerosis

New AI Tool Reveals Genetic Link Between Memory Cells and Alzheimer’s

Ketamine Fails to Outperform Placebo in Major Depression Trial

Hungry Brain Rewrites Emotional Priorities

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