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Parkinson’s disease

·April 16, 2025·5 min read

AI Tool Predicts Toxic Protein Structures Behind Brain Disorders

A new AI tool called RibbonFold is revolutionizing how scientists understand misfolded proteins linked to Alzheimer’s and Parkinson’s. Unlike existing tools such as AlphaFold, which predict correctly folded proteins, RibbonFold is specifically designed to model the twisted, ribbonlike shapes of amyloid fibrils that accumulate in neurodegenerative diseases.

Brain Cancer Featured Genetics Neurology Neuroscience

·April 14, 2025·4 min read

Shared Protein Link Found Between Parkinson’s and Cancer

A new study reveals that the protein alpha-synuclein, known for its role in Parkinson’s disease, also contributes to the development of melanoma by promoting excessive DNA repair and cell proliferation. While in neurons, excess alpha-synuclein leads to cell death, in melanoma cells it enables uncontrolled growth by recruiting repair proteins to DNA breaks.

Featured Genetics Neuroscience

·April 12, 2025·5 min read

New Genes Linked to Parkinson’s Risk Revealed

Researchers have long wondered why some people with high-risk Parkinson’s gene variants develop the disease while others don’t. A new study has uncovered that additional genetic players, particularly the Commander gene complex, influence whether the disease manifests.

Autism Featured Genetics Neurology Neuroscience

·March 7, 2025·4 min read

Genetic Variant in ITSN1 Linked to Higher Parkinson’s and ASD Risk

A new study has identified genetic variants in the ITSN1 gene that significantly increase the risk of developing Parkinson’s disease. Researchers analyzed nearly 500,000 genetic profiles and found that individuals carrying ITSN1 variants face up to a tenfold higher risk of Parkinson’s.

Featured Neurology Neuroscience

·February 25, 2025·4 min read

FDA Approves Adaptive DBS for Parkinson’s Patients

The FDA has approved adaptive deep brain stimulation (aDBS), a breakthrough therapy that adjusts in real time to Parkinson’s disease symptoms. Unlike traditional DBS, which delivers constant stimulation, aDBS monitors brain activity and responds with precise electric pulses to prevent stiffness and involuntary movements.

Auditory Neuroscience Featured Neurology Neuroscience

·January 14, 2025·5 min read

Hearing Loss May Signal Increased Risk of Parkinson’s Disease

A new study has identified a potential link between hearing impairment and an increased risk of developing Parkinson’s disease. Researchers analyzed data from over 159,000 individuals, finding that every 10-decibel increase in hearing loss corresponded to a 57% higher risk of Parkinson’s.

Featured Neurology Neuroscience

·January 3, 2025·5 min read

Ketamine Offers Hope for Parkinson’s Treatment-Linked Dyskinesia

Researchers have uncovered a new understanding of levodopa-induced dyskinesia, a common side effect in Parkinson’s patients, revealing that the motor cortex disconnects rather than directly causing these movements.

Featured Neurology Neuroscience

·December 16, 2024·4 min read

Accurate Parkinson’s Detection via Emotional Brain Responses

A new study has achieved near-perfect accuracy in detecting Parkinson's disease by analyzing brain responses to emotional stimuli using EEG and AI. Researchers found that Parkinson's patients process emotions differently, struggling with recognizing fear, disgust, and surprise and focusing more on emotional intensity than valence.

This shows chemical imaging of the microbiome.

Featured Neurology Neuroscience

·November 21, 2024·5 min read

Parkinson’s Medication Alters Microbiome, Induces Iron Deficiency

The Parkinson's drug entacapone disrupts the gut microbiome by inducing iron deficiency, favoring the growth of potentially harmful bacteria like E. coli. Using advanced molecular techniques, researchers identified that entacapone interferes with iron availability, a critical resource for many gut microbes.

Featured Neurology Neuroscience

·November 18, 2024·7 min read

Parkinson’s Tremor Linked to Dopamine in Caudate Nucleus

Rest tremor in Parkinson’s disease is linked to dopamine activity in the caudate nucleus, challenging conventional beliefs about dopamine loss and motor symptoms. Surprisingly, patients with stronger tremor preserved more dopamine in the caudate, highlighting a complex relationship between tremor severity and neural circuits.

Featured Genetics Neurology Neuroscience

·November 13, 2024·6 min read

Parkinson’s Progression Linked to New Protein Pathway

Researchers have identified a protein, TMEM16F, that appears to aid the spread of Parkinson’s pathology in the brain. They found that a mutation in this protein promotes the secretion of a harmful form of α-synuclein, which moves through nerve cells, forming toxic Lewy bodies.

Featured Genetics Neurology Neuroscience

·November 3, 2024·3 min read

RNA Structures Linked to Parkinson’s Protein Aggregates

Researchers have identified unique RNA structures called G-quadruplexes (G4s) that promote harmful α-synuclein protein aggregation linked to neurodegenerative diseases like Parkinson’s. Elevated calcium levels trigger these G4s, acting as "scaffolds" for α-synuclein clumping. Administering 5-aminolevulinic acid (5-ALA) to model mice prevented aggregation and reduced motor symptoms. This breakthrough suggests that G4-targeted therapies could offer early intervention for neurodegenerative diseases.

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Parkinson’s disease

AI Tool Predicts Toxic Protein Structures Behind Brain Disorders

Shared Protein Link Found Between Parkinson’s and Cancer

New Genes Linked to Parkinson’s Risk Revealed

Genetic Variant in ITSN1 Linked to Higher Parkinson’s and ASD Risk

FDA Approves Adaptive DBS for Parkinson’s Patients

Hearing Loss May Signal Increased Risk of Parkinson’s Disease

Ketamine Offers Hope for Parkinson’s Treatment-Linked Dyskinesia

Accurate Parkinson’s Detection via Emotional Brain Responses

Parkinson’s Medication Alters Microbiome, Induces Iron Deficiency

Parkinson’s Tremor Linked to Dopamine in Caudate Nucleus

Parkinson’s Progression Linked to New Protein Pathway

RNA Structures Linked to Parkinson’s Protein Aggregates

AI Reveals What Keeps People Committed to Exercise

Disrupted Myelin Protein Implicated in Schizophrenia

Potential Depression Risk Linked to Ozempic-Like Drugs

Negative Distractions Most Disrupt Attention and Linger in Memory

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